Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297908 | 0.82 | TP53 (0.36) | TP53TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL3901257 | 0.82 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4464586 | 0.76 | TDP1 (0.44) | TP53TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2058773 | 0.75 | ALDH1A1 (0.39) | TP53TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL1357184 | 0.75 | TP53 (0.37) | TP53TDP1ALDH1A1TSHRPTGS2 | |
| SCHEMBL10454538 | 0.73 | TP53 (0.38) | TP53TDP1ALDH1A1TSHRPTGS2 | |
| SCHEMBL1357315 | 0.70 | TP53 (0.37) | TP53TDP1PTGS2 | |
| SCHEMBL2394506 | 0.69 | ALDH1A1 (0.70) | TP53TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL29547473 | 0.69 | ALDH1A1 (0.70) | TP53TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL9331235 | 0.68 | ALDH1A1 (0.42) | TP53TDP1ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1396504-B1 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | MITSUI CHEMICALS INC (JP) | 2009-01-14 | — | — | EP | disclosed |
| US-7067587-B2 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | MITSUI CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20040242791-A1 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | MITSUI CHEMICALS, INC. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1396504-A2 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | Mitsui Chemicals, Inc. (JP) | 2004-03-10 | — | — | EP | disclosed |