SCHEMBL3890773

SCHEMBL3890773

Cc1ccc(S(=O)(=O)c2ccccc2C(=O)CCl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.45
MMP9 P14780 6/20 0.45
MMP8 P22894 6/20 0.45
MMP12 P39900 6/20 0.45
MMP13 P45452 6/20 0.45
MMP14 P50281 6/20 0.45
MMP16 P51512 6/20 0.45
MMP3 P08254 4/20 0.44
MMP1 P03956 3/20 0.44
RECQL P46063 1/20 0.44
GAA P10253 1/20 0.44
HSD11B1 P28845 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alanine SCHEMBL11038489 0.91 MMP2 (0.43) MMP2MMP9MMP8MMP12MMP13
SCHEMBL9626817 0.86 RECQL (0.47) MMP2MMP9MMP8MMP12MMP13
SCHEMBL22652933 0.83 GAA (0.48) MMP2MMP9MMP8MMP12MMP13
SCHEMBL13908249 0.81 MMP2 (0.53) MMP2MMP9MMP8MMP12MMP13
SCHEMBL5331978 0.80 HTR2A (0.51) MMP2MMP9MMP8MMP12MMP13
SCHEMBL8988719 0.79 CA1 (0.59) MMP2MMP9MMP8MMP12MMP13
SCHEMBL11853033 0.76 GAA (0.68) GAAHSD11B1L3MBTL1HTTSMN1; SMN2
SCHEMBL31000980 0.76 GAA (0.68) GAAHSD11B1L3MBTL1HTTSMN1; SMN2
SCHEMBL9772295 0.76 CNR2 (0.48) MMP2MMP9MMP8MMP12MMP13
SCHEMBL3890776 0.76 GAA (0.57) RECQLGAAHSD11B1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10307505-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2019-06-04 US claimed
US-20170333592-A1 Wound Dressings For The Controlled Release Of Therapeutic Agents SYSTAGENIX WOUND MANAGEMENT, LIMITED (GB) 2017-11-23 US claimed
US-9687581-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2017-06-27 US claimed
US-20150098985-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC KCI USA, INC. 2015-04-09 US claimed
US-8858987-B2 Wound dressing for the controlled release of therapeutic agents SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) 2014-10-14 US claimed
EP-1687039-B1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON INC (US) 2009-01-28 EP claimed
US-20070148214-A1 Wound dressing for the controlled release of therapeutic agents KCI USA, INC. 2007-06-28 US claimed
EP-1687039-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON, INC. (US) 2006-08-09 EP claimed
WO-2005051441-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON, INC. (US) 2005-06-09 WO claimed
US-20200221753-A1 TEXTURED INGESTIBLE PRODUCTS EETBE INC (US) 2020-07-16 US disclosed
US-10307505-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2019-06-04 US disclosed
US-20170333592-A1 Wound Dressings For The Controlled Release Of Therapeutic Agents SYSTAGENIX WOUND MANAGEMENT, LIMITED (GB) 2017-11-23 US disclosed
US-20170196253-A1 TEXTURED INGESTIBLE PRODUCTS EETBE, INC. 2017-07-13 US disclosed
US-9687581-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2017-06-27 US disclosed
WO-2005051441-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON, INC. (US) 2005-06-09 WO disclosed
US-20040166530-A1 F-box proteins and genes HARPER JEFFREY WADE (US) 2004-08-26 US disclosed
WO-2004041179-A2 SCAVENGER RECEPTOR B1 (CLA-1) TARGETING FOR THE TREATMENT OF INFECTION, SEPSIS AND INFLAMMATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NIH (US) 2004-05-21 WO disclosed
US-6573094-B1 Identification of components of E3 complex involved in ubiquitination of cell cycle regulator proteins, including a class of proteins that directly function in recognition of ubiquitination targets; use for drug discovery and assessment BAYLOR COLLEGE OF MEDICINE 2003-06-03 US disclosed
US-6232081-B1 COMPLEXING WITH SLIMB PROTEIN BAYLOR COLLEGE OF MEDICINE 2001-05-15 US disclosed
US-5328844-A Amino acid nutrients UNIVERSITY OF COLORADO FOUNDATION, INC. (US) 1994-07-12 US disclosed