SCHEMBL3890776

SCHEMBL3890776

Cc1ccc(S(=O)(=O)c2ccc(C(=O)CCl)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.57
KMT2A Q03164 3/20 0.53
GSK3B P49841 3/20 0.50
RECQL P46063 1/20 0.50
HSD11B1 P28845 1/20 0.50
PAX8 Q06710 1/20 0.49
LMNA P02545 1/20 0.49
PKM P14618 3/20 0.49
ALDH1A1 P00352 3/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
HIF1A Q16665 2/20 0.47
TRPA1 O75762 1/20 0.47
MAPK1 P28482 1/20 0.47
PRMT1 Q99873 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846835 0.87 GSK3B (0.64) GAAKMT2AGSK3BLMNAPKM
SCHEMBL7311605 0.79 GAA (0.64) GAAKMT2ALMNAPKMALDH1A1
SCHEMBL10831304 0.79 GSR (0.59) KMT2AGSK3BALDH1A1HIF1ATRPA1
SCHEMBL7316384 0.77 ALDH1A1 (0.71) GAAKMT2ARECQLPKMALDH1A1
SCHEMBL3773485 0.77 GAA (0.67) GAAKMT2ALMNAPKMALDH1A1
SCHEMBL10476894 0.76 GAA (0.80) GAAKMT2APKMALDH1A1CA12
SCHEMBL3890773 0.76 MMP2 (0.45) GAAKMT2ARECQLHSD11B1CA1
SCHEMBL10067072 0.76 GAA (1.00) GAAKMT2ALMNAPKMALDH1A1
SCHEMBL11480265 0.76 GSK3B (0.80) KMT2AGSK3BALDH1A1HIF1ATRPA1
SCHEMBL4400955 0.76 GAA (1.00) GAAKMT2ALMNAPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10307505-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2019-06-04 US claimed
US-20170333592-A1 Wound Dressings For The Controlled Release Of Therapeutic Agents SYSTAGENIX WOUND MANAGEMENT, LIMITED (GB) 2017-11-23 US claimed
US-9687581-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2017-06-27 US claimed
US-20150098985-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC KCI USA, INC. 2015-04-09 US claimed
US-8858987-B2 Wound dressing for the controlled release of therapeutic agents SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) 2014-10-14 US claimed
EP-1687039-B1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON INC (US) 2009-01-28 EP claimed
US-20070148214-A1 Wound dressing for the controlled release of therapeutic agents KCI USA, INC. 2007-06-28 US claimed
EP-1687039-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON, INC. (US) 2006-08-09 EP claimed
WO-2005051441-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON, INC. (US) 2005-06-09 WO claimed
US-20200221753-A1 TEXTURED INGESTIBLE PRODUCTS EETBE INC (US) 2020-07-16 US disclosed
US-10307505-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2019-06-04 US disclosed
US-20170333592-A1 Wound Dressings For The Controlled Release Of Therapeutic Agents SYSTAGENIX WOUND MANAGEMENT, LIMITED (GB) 2017-11-23 US disclosed
US-20170196253-A1 TEXTURED INGESTIBLE PRODUCTS EETBE, INC. 2017-07-13 US disclosed
US-9687581-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2017-06-27 US disclosed
WO-2004041179-A2 SCAVENGER RECEPTOR B1 (CLA-1) TARGETING FOR THE TREATMENT OF INFECTION, SEPSIS AND INFLAMMATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NIH (US) 2004-05-21 WO disclosed
US-6573094-B1 Identification of components of E3 complex involved in ubiquitination of cell cycle regulator proteins, including a class of proteins that directly function in recognition of ubiquitination targets; use for drug discovery and assessment BAYLOR COLLEGE OF MEDICINE 2003-06-03 US disclosed
WO-2000063350-A9 CYSTEINE PROTEASE AND INHIBITORS FOR PREVENTION AND TREATMENT OF NEUROCYSTICEROCOSIS UNIV GEORGIA RES FOUND (US) 2002-06-13 WO disclosed
US-6232081-B1 COMPLEXING WITH SLIMB PROTEIN BAYLOR COLLEGE OF MEDICINE 2001-05-15 US disclosed
WO-2000063350-A2 CYSTEINE PROTEASE AND INHIBITORS FOR PREVENTION AND TREATMENT OF NEUROCYSTICEROCOSIS THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2000-10-26 WO disclosed
US-5328844-A Amino acid nutrients UNIVERSITY OF COLORADO FOUNDATION, INC. (US) 1994-07-12 US disclosed