Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | MMP8 | P22894 | 5/20 | 0.48 |
| ▸ | MMP12 | P39900 | 5/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.48 |
| ▸ | MMP14 | P50281 | 5/20 | 0.48 |
| ▸ | MMP16 | P51512 | 5/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901415 | 0.88 | L3MBTL1 (0.44) | HTR2AHTR2CGAAL3MBTL1MMP2 | |
| SCHEMBL364480 | 0.86 | HTR6 (0.55) | HTR2AHTR2CGAAMMP2MMP9 | |
| SCHEMBL13908249 | 0.85 | MMP2 (0.53) | GAAL3MBTL1MMP2MMP9MMP8 | |
| SCHEMBL27492085 | 0.85 | HTR6 (0.54) | HTR2AHTR2CMMP2MMP9MMP8 | |
| SCHEMBL31061277 | 0.83 | HTR2A (0.51) | HTR2AHTR2CMMP2MMP9MMP8 | |
| SCHEMBL22652933 | 0.83 | GAA (0.48) | GAAL3MBTL1MMP2MMP9MMP8 | |
| SCHEMBL8988719 | 0.83 | CA1 (0.59) | GAAL3MBTL1MMP2MMP9MMP8 | |
| Potassium SCHEMBL31176741 | 0.82 | HTR2A (0.63) | HTR2AHTR2CGAAMMP2MMP9 | |
| SCHEMBL9626817 | 0.81 | RECQL (0.47) | GAAL3MBTL1MMP2MMP9MMP8 | |
| SCHEMBL25302092 | 0.80 | HTR2A (0.48) | HTR2AHTR2CMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569617-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | Kos Life Sciences, Inc. (US) | 2005-09-07 | — | — | EP | claimed |
| WO-2004022035-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | KOS PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | WO | claimed |
| WO-2002007672-A2 | A MEDICINAL AEROSOL FORMULATION | AEROPHARM TECHNOLOGY, INC. (US) | 2002-01-31 | — | — | WO | claimed |
| US-4307170-A | ACID CATALYST - AZO COUPLERS PROMOTE DISCOLORATION AND BLOOM RESISTANCE | JAMES RIVER GRAPHICS, INC. (US) | 1981-12-22 | — | — | US | claimed |
| CN-116478181-B | Catalytic synthesis method of chiral oxazoline compound | 中国海洋大学 | 2024-05-17 | — | — | CN | disclosed |
| EP-4340828-A1 | QUERCETIN-CONTAINING COMPOSITIONS FOR USE IN TREATING AMYOTROPHIC LATERAL SCLEROSIS | Quercis Pharma AG (CH) | 2024-03-27 | — | — | EP | disclosed |
| CN-116478181-A | Catalytic synthesis method of chiral oxazoline compound | 中国海洋大学 | 2023-07-25 | — | — | CN | disclosed |
| WO-2022243942-A1 | QUERCETIN-CONTAINING COMPOSITIONS FOR USE IN TREATING AMYOTROPHIC LATERAL SCLEROSIS | Quercis Pharma AG (CH) | 2022-11-24 | — | — | WO | disclosed |
| WO-2022170075-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | CORTEVA AGRISCIENCE LLC (US) | 2022-08-11 | — | — | WO | disclosed |
| US-10669242-B2 | Clostridium difficile toxin inhibitors | Venenum Biodesign, LLC (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190194147-A1 | Novel Clostridium Difficile Toxin Inhibitors | Venenum Biodesign, LLC (US) | 2019-06-27 | — | — | US | disclosed |
| EP-1745056-A4 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY CORP (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-1745056-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | Yale University Corporation (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005111050-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY (US) | 2005-11-24 | — | — | WO | disclosed |
| EP-1569617-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | Kos Life Sciences, Inc. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004022035-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | KOS PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
| WO-2002015883-A1 | A METHOD OF STABILIZING A DRY POWDER PHARMACEUTICAL FORMULATION | AEROPHARM TECHNOLOGY INCORPORATED (US) | 2002-02-28 | — | — | WO | disclosed |
| WO-2002007672-A2 | A MEDICINAL AEROSOL FORMULATION | AEROPHARM TECHNOLOGY, INC. (US) | 2002-01-31 | — | — | WO | disclosed |
| US-4307170-A | ACID CATALYST - AZO COUPLERS PROMOTE DISCOLORATION AND BLOOM RESISTANCE | JAMES RIVER GRAPHICS, INC. (US) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194147-A1 | Novel Clostridium Difficile Toxin Inhibitors | GABRA5, GABRA1, GABRA4 | HTR2A 1936/4885HTR2C 1617/4885GAA 1644/4885 |
| US-10669242-B2 | Clostridium difficile toxin inhibitors | GABRA5, GABRA1, GABBR2 | HTR2A 1420/4885HTR2C 1166/4885GAA 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.