Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.36 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890870 | 1.00 | THRA (0.43) | THRATHRBFFAR4FFAR1CHRNA7 | |
| SCHEMBL3888377 | 0.99 | THRA (0.45) | THRATHRBFFAR4FFAR1CHRNA7 | |
| SCHEMBL3888373 | 0.99 | THRA (0.45) | THRATHRBFFAR4FFAR1CHRNA7 | |
| SCHEMBL3882421 | 0.92 | CHRNA7 (0.37) | THRATHRBFFAR4CHRNA7CCNC | |
| SCHEMBL3883543 | 0.91 | CHRNA7 (0.36) | THRATHRBCHRNA7CCNCCDK8 | |
| SCHEMBL3896107 | 0.90 | THRB (0.42) | THRATHRBFFAR4FFAR1PPARD | |
| SCHEMBL3896105 | 0.90 | THRB (0.42) | THRATHRBFFAR4FFAR1PPARD | |
| SCHEMBL3883910 | 0.89 | THRB (0.43) | THRATHRBFFAR4FFAR1PPARD | |
| SCHEMBL3883914 | 0.89 | THRB (0.43) | THRATHRBFFAR4FFAR1PPARD | |
| SCHEMBL3888709 | 0.89 | FFAR4 (0.37) | FFAR4FFAR1CHRNA7CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |