Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896105 | 1.00 | THRB (0.42) | THRBTHRAFFAR4POLBFAAH | |
| SCHEMBL3883914 | 0.99 | THRB (0.43) | THRBTHRAFFAR4POLBFAAH | |
| SCHEMBL3883910 | 0.99 | THRB (0.43) | THRBTHRAFFAR4POLBFAAH | |
| SCHEMBL3890231 | 0.92 | FAAH (0.35) | THRBTHRAFFAR4POLBFAAH | |
| SCHEMBL3888424 | 0.91 | FAAH (0.37) | THRBTHRAFFAR4POLBFAAH | |
| SCHEMBL3890870 | 0.90 | THRA (0.43) | THRBTHRAFFAR4PPARDPPARA | |
| SCHEMBL3890876 | 0.90 | THRA (0.43) | THRBTHRAFFAR4PPARDPPARA | |
| SCHEMBL3888373 | 0.89 | THRA (0.45) | THRBTHRAFFAR4PPARDPPARA | |
| SCHEMBL3888377 | 0.89 | THRA (0.45) | THRBTHRAFFAR4PPARDPPARA | |
| SCHEMBL3890229 | 0.88 | FFAR4 (0.34) | THRBFFAR4POLBFAAHPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |