Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891311 | 1.00 | BLM (0.56) | BLMSMN1; SMN2HIF1AFNTAFNTB | |
| SCHEMBL14935688 | 0.86 | SMN1; SMN2 (0.56) | BLMSMN1; SMN2HIF1ACYP1A2CYP3A4 | |
| SCHEMBL28243868 | 0.86 | SMN1; SMN2 (0.56) | BLMSMN1; SMN2HIF1ACYP1A2CYP3A4 | |
| SCHEMBL4362988 | 0.86 | SMN1; SMN2 (0.56) | BLMSMN1; SMN2HIF1ACYP1A2CYP3A4 | |
| SCHEMBL7387615 | 0.74 | BLM (0.67) | BLMSMN1; SMN2HIF1AFNTAFNTB | |
| SCHEMBL7795287 | 0.73 | SMN1; SMN2 (0.49) | BLMSMN1; SMN2HIF1ASLC7A5ALDH1A1 | |
| SCHEMBL28664390 | 0.73 | BLM (0.44) | BLMFNTAFNTBCA2ESR1 | |
| SCHEMBL28966331 | 0.73 | BLM (0.65) | BLMSMN1; SMN2HIF1AFNTAFNTB | |
| SCHEMBL17768418 | 0.73 | BLM (0.65) | BLMSMN1; SMN2HIF1AFNTAFNTB | |
| SCHEMBL24253146 | 0.72 | BLM (0.62) | BLMSMN1; SMN2HIF1AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200222492-A1 | Method of Reducing Injury to Mammalian Cells | NONO INC. (CA) | 2020-07-16 | — | — | US | disclosed |
| US-20180369319-A1 | Method of Reducing Injury to Mammalian Cells | NONO INC (CA) | 2018-12-27 | — | — | US | disclosed |
| US-20170239316-A1 | Method Of Reducing Injury To Mammalian Cells | NONO INC (CA) | 2017-08-24 | — | — | US | disclosed |
| US-20150190459-A1 | Method Of Reducing Injury To Mammalian Cells | NONO INC (CA) | 2015-07-09 | — | — | US | disclosed |
| US-20120302504-A1 | Method Of Reducing Injury To Mammalian Cells | NONO, INC. (CA) | 2012-11-29 | — | — | US | disclosed |
| US-8071548-B2 | Method of reducing injury to mammalian cells | NONO, INC. (CA) | 2011-12-06 | — | — | US | disclosed |
| US-20090281037-A1 | Method of Reducing Injury to Mammalian Cells | NONO INC. (CA) | 2009-11-12 | — | — | US | disclosed |
| US-7510824-B2 | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord | NONO INC. (CA) | 2009-03-31 | — | — | US | disclosed |
| US-20050059597-A1 | Method of reducing injury to mammalian cells | 2056954 ONTARIO LTD. (CA) | 2005-03-17 | — | — | US | disclosed |