SCHEMBL7795287

SCHEMBL7795287

CC(=O)C(N)(Cc1ccccc1)[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.49
HIF1A Q16665 1/20 0.49
SLC6A2 P23975 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CPA1 P15085 3/20 0.38
ALDH1A1 P00352 4/20 0.38
RECQL P46063 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38
ARG1 P05089 1/20 0.37
ARG2 P78540 1/20 0.37
MAPK1 P28482 1/20 0.37
ALPI P09923 1/20 0.37
PKM P14618 1/20 0.37
PTGS1 P23219 1/20 0.37
XIAP P98170 1/20 0.37
SLC7A5 Q01650 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4362988 0.86 SMN1; SMN2 (0.56) SMN1; SMN2HIF1ASLC6A2TAAR1CES2
SCHEMBL14935688 0.86 SMN1; SMN2 (0.56) SMN1; SMN2HIF1ASLC6A2TAAR1CES2
SCHEMBL28243868 0.86 SMN1; SMN2 (0.56) SMN1; SMN2HIF1ASLC6A2TAAR1CES2
SCHEMBL10831201 0.75 SLC6A2 (0.55) SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1
Acetic Acid SCHEMBL5573467 0.75 SMN1; SMN2 (0.44) SMN1; SMN2HIF1ASLC6A2TAAR1CPA1
SCHEMBL8762142 0.75 TRPA1 (0.46) SMN1; SMN2HIF1ASLC6A2TAAR1CPA1
SCHEMBL7797910 0.75 TRPA1 (0.46) SMN1; SMN2HIF1ASLC6A2TAAR1CPA1
SCHEMBL3891306 0.73 BLM (0.56) SMN1; SMN2HIF1AALDH1A1RECQLCYP3A4
SCHEMBL3891311 0.73 BLM (0.56) SMN1; SMN2HIF1AALDH1A1RECQLCYP3A4
SCHEMBL10078943 0.73 SLC6A2 (0.57) SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1159253-A2 SYNTHESIS OF NITROALCOHOL DIASTEREOMERS Johnson Matthey Pharmaceutical Materials Inc (US) 2001-12-05 EP claimed
WO-2000050378-A9 SYNTHESIS OF NITROALCOHOL DIASTEREOMERS 2001-08-23 WO claimed
WO-2000050378-A2 SYNTHESIS OF NITROALCOHOL DIASTEREOMERS PHARM-ECO LABORATORIES, INC. (US) 2000-08-31 WO claimed
EP-1159253-A2 SYNTHESIS OF NITROALCOHOL DIASTEREOMERS Johnson Matthey Pharmaceutical Materials Inc (US) 2001-12-05 EP disclosed
WO-2000050378-A9 SYNTHESIS OF NITROALCOHOL DIASTEREOMERS 2001-08-23 WO disclosed
WO-2000050378-A2 SYNTHESIS OF NITROALCOHOL DIASTEREOMERS PHARM-ECO LABORATORIES, INC. (US) 2000-08-31 WO disclosed
EP-0769003-A1 AMINO ACID-DERIVED DIAMINOPROPANOLS Pharmeco Laboratories, Inc. (US) 1997-04-23 EP disclosed