Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | NPY1R | P25929 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
| ▸ | FURIN | P09958 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996377 | 0.75 | ALDH1A1 (0.42) | ALDH1A1SLC1A2MEN1KMT2ACA9 | |
| SCHEMBL3887727 | 0.75 | ALDH1A1 (0.42) | ALDH1A1SLC1A2MEN1KMT2ACA9 | |
| SCHEMBL11996378 | 0.75 | ALDH1A1 (0.42) | ALDH1A1SLC1A2MEN1KMT2ACA9 | |
| SCHEMBL3887725 | 0.72 | ALDH1A1 (0.39) | ALDH1A1SLC1A2MEN1KMT2ACA9 | |
| SCHEMBL28704993 | 0.69 | CA9 (0.50) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996382 | 0.66 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996383 | 0.66 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL22127960 | 0.66 | SIRT1 (0.40) | MEN1KMT2A | |
| SCHEMBL12509123 | 0.61 | SIRT1 (0.34) | — | |
| SCHEMBL23460325 | 0.60 | NPY1R (0.48) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |