SCHEMBL3897205

SCHEMBL3897205

c1ccc(Sc2ccccc2Sc2ccc(Sc3ccccc3Sc3ccccc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.52
MAPT P10636 3/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.50
NSD2 O96028 1/20 0.50
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
HPGD P15428 5/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MGLL Q99685 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46
TUBB3 Q13509 1/20 0.46
TUBB2A Q13885 1/20 0.46
TUBB8 Q3ZCM7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3892294 0.97 MAOA (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL11119109 0.97 MAOA (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL795029 0.97 SIRT1 (0.54) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3900082 0.94 SIRT1 (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3897215 0.94 SIRT1 (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL4869740 0.87 MAOA (0.48) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3904203 0.86 MAPT (0.50) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3889771 0.84 MAPT (0.48) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL10533879 0.84 SIRT1 (0.45) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3895279 0.84 MAPT (0.48) SIRT1MAPTMAPK1KDM4ENSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7468229-B2 Polyphenyl thioether and thiophosphate containing photoconductors XEROX CORPORATION (US) 2008-12-23 US claimed
US-7462432-B2 Extended lifetimes of service in excess of about 3,500,000 imaging cycles; excellent electronic characteristics; stable electrical properties; low image ghosting; resistance to charge transport layer cracking upon exposure to the vapor of certain solvents; surface characteristics, wear resistance XEROX CORPORATION (US) 2008-12-09 US claimed
US-20070292791-A1 Polyphenyl thioether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292785-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292790-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US disclosed
US-7507510-B2 Polyphenyl ether phosphate containing photoconductors XEROX CORPORATION (US) 2009-03-24 US disclosed
US-7498108-B2 Thiophosphate containing photoconductors XEROX CORPORATION (US) 2009-03-03 US disclosed
US-7491480-B2 Thiophosphate and antioxidant containing photoconductors XEROX CORPORATION (US) 2009-02-17 US disclosed
US-7479358-B2 Ether and thiophosphate containing photoconductors XEROX CORPORATION (US) 2009-01-20 US disclosed
US-7476478-B2 Polyphenyl thioether and antioxidant containing photoconductors XEROX CORPORATION (US) 2009-01-13 US disclosed
US-7476477-B2 Thiophosphate containing photoconductors XEROX CORPORATION (US) 2009-01-13 US disclosed
US-20070292789-A1 Polyphenyl ether containing photoconductors XEROX CORPORATION 2007-12-20 US disclosed
US-20070292787-A1 Flexible imaging member such as a belt including a photogenerating layer and a charge transport mixture of an antioxidant and a polyphenyl thioether that may contain phenoxy groups, e.g., 1-phenoxy-3-[[3-(phenylthio)phenyl]thio]benzene; increased surface hardness, wear resistance and solvent resistance XEROX CORPORATION 2007-12-20 US disclosed
US-20070292791-A1 Polyphenyl thioether containing photoconductors XEROX CORPORATION 2007-12-20 US disclosed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US disclosed
US-20070026233-A1 Photoreceptor layer having polyether lubricants XEROX CORPORATION 2007-02-01 US disclosed
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed