SCHEMBL795029

SCHEMBL795029

c1ccc(Sc2ccccc2Sc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.54
MAPT P10636 4/20 0.52
MAPK1 P28482 2/20 0.52
KDM4E B2RXH2 2/20 0.52
NSD2 O96028 1/20 0.52
HPGD P15428 5/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MGLL Q99685 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TUBB4A P04350 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48
TUBA4A P68366 1/20 0.48
TUBB4B P68371 1/20 0.48
TUBB3 Q13509 1/20 0.48
TUBB2A Q13885 1/20 0.48
TUBB8 Q3ZCM7 1/20 0.48
TUBA3E Q6PEY2 1/20 0.48
TUBA1A Q71U36 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900082 0.97 SIRT1 (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3897205 0.97 SIRT1 (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3897215 0.97 SIRT1 (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3892294 0.94 MAOA (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL11119109 0.94 MAOA (0.52) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3904203 0.89 MAPT (0.50) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3889771 0.87 MAPT (0.48) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL10533879 0.87 SIRT1 (0.45) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL3895279 0.87 MAPT (0.48) SIRT1MAPTMAPK1KDM4ENSD2
SCHEMBL30958577 0.85 MAPT (0.57) SIRT1MAPTMAPK1KDM4ENSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9604941-B2 Preparation method of conjugated compound containing bis(phenylsulfonyl)benzene structure and an organic electroluminescent diode device using the conjugated compound SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2017-03-28 US claimed
US-20160322567-A1 CONJUGATED COMPOUND CONTAINING BIS(PHENYLSULFONYL)BENZENE STRUCTURE, PREPARATION METHOD AND APPLICATION THEREOF SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2016-11-03 US claimed
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US claimed
US-7468229-B2 Polyphenyl thioether and thiophosphate containing photoconductors XEROX CORPORATION (US) 2008-12-23 US claimed
US-7462432-B2 Extended lifetimes of service in excess of about 3,500,000 imaging cycles; excellent electronic characteristics; stable electrical properties; low image ghosting; resistance to charge transport layer cracking upon exposure to the vapor of certain solvents; surface characteristics, wear resistance XEROX CORPORATION (US) 2008-12-09 US claimed
US-7427440-B2 Photoreceptor layer having polyether lubricants XEROX CORPORATION (US) 2008-09-23 US claimed
US-20070292791-A1 Polyphenyl thioether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292785-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292790-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US claimed
US-20070026233-A1 Photoreceptor layer having polyether lubricants XEROX CORPORATION 2007-02-01 US claimed
US-4619961-A FIREPROOFING ETHYL CORPORATION (US) 1986-10-28 US claimed
CN-116657163-A Method for dithioating o-dihalogenated aromatic hydrocarbon 河南大学 2023-08-29 CN disclosed
US-11703760-B2 Fluorocarboxylic acid-containing monomer, fluorocarboxylic acid-containing polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
CN-113820920-A Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2021-12-21 CN disclosed
CN-107107389-B Method for producing a densified polymer powder, and method for melt-processing a densified polymer powder 沙特基础工业全球技术有限公司 2020-05-19 CN disclosed
EP-0279217-A1 Process for the preparation of poly(arylensulfides) with adjustable melt viscosity BAYER AG (DE) 1988-08-24 EP disclosed
US-4619961-A FIREPROOFING ETHYL CORPORATION (US) 1986-10-28 US disclosed
US-4426500-A DEPOLYMERIZATION OF POLYTHIOETHERS, CLEANING DEPOSITS PHILLIPS PETROLEUM COMPANY (US) 1984-01-17 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160322567-A1 CONJUGATED COMPOUND CONTAINING BIS(PHENYLSULFONYL)BENZENE STRUCTURE, PREPARATION METHOD AND APPLICATION THEREOF AOC1, DDT, KCNJ1 SIRT1 1979/4885MAPT 2806/4885MAPK1 2308/4885
US-11703760-B2 Fluorocarboxylic acid-containing monomer, fluorocarboxylic acid-containing polymer, resist composition and patterning process NAF1, PFN1, COL1A1 SIRT1 4267/4885MAPT 1210/4885MAPK1 837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.