Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253880 | 0.80 | HTT (0.53) | KMT2ATSHRPOLBPTGDR2HTT | |
| SCHEMBL8752451 | 0.79 | ALDH1A1 (0.63) | KMT2ATSHRPOLBHTTMEN1 | |
| SCHEMBL27647760 | 0.78 | CYTH2 (0.53) | KMT2AHTTMEN1ALDH1A1LMNA | |
| SCHEMBL9568785 | 0.77 | PTGDR2 (0.48) | KMT2ATSHRPOLBPTGDR2HTT | |
| SCHEMBL24260332 | 0.77 | HSD17B10 (0.46) | KMT2AACLYPOLBMEN1ALDH1A1 | |
| SCHEMBL3380247 | 0.77 | POLB (0.68) | KMT2APOLBHTTMEN1ALDH1A1 | |
| SCHEMBL360590 | 0.76 | MAPT (0.49) | KMT2AACLYHTTMEN1ALDH1A1 | |
| SCHEMBL28139674 | 0.75 | KMT2A (0.68) | KMT2ATSHRHTTKCNA5MEN1 | |
| SCHEMBL21771948 | 0.74 | GAA (0.55) | KMT2ATSHRPOLBHTTMEN1 | |
| SCHEMBL24260545 | 0.74 | HSD17B10 (0.44) | KMT2AACLYPOLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |