SCHEMBL360590

SCHEMBL360590

CCC(=O)Oc1ccccc1Nc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.49
ALOX15 P16050 1/20 0.49
GAA P10253 3/20 0.46
ELANE P08246 1/20 0.44
FABP4 P15090 1/20 0.44
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
ACLY P53396 1/20 0.43
ALDH1A1 P00352 4/20 0.42
HSP90AA1 P07900 1/20 0.42
ATM Q13315 1/20 0.42
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GFER P55789 1/20 0.41
NGLY1 Q96IV0 1/20 0.41
FABP1 P07148 1/20 0.41
HTT P42858 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL361663 0.81 MAPT (0.59) MAPTALOX15GAAFABP4AKR1C3
SCHEMBL24260332 0.81 HSD17B10 (0.46) ALOX15GAAELANEHSD17B10KMT2A
SCHEMBL1360923 0.81 MAPT (0.51) MAPTALOX15GAAFABP4AKR1C3
SCHEMBL21725058 0.79 CXCL8 (0.51) GAAAKR1C3KMT2AMAPK1
SCHEMBL9480176 0.79 MAPT (0.65) MAPTALOX15GAAFABP4HSD17B10
SCHEMBL21771948 0.79 GAA (0.55) MAPTGAAHSD17B10KMT2AMEN1
SCHEMBL24260545 0.79 HSD17B10 (0.44) ALOX15GAAELANEHSD17B10KMT2A
SCHEMBL27596581 0.79 HSD17B10 (0.68) MAPTGAAHSD17B10KMT2AALDH1A1
SCHEMBL8435546 0.78 ALOX15 (0.55) MAPTALOX15ELANEHSD17B10KMT2A
SCHEMBL11213579 0.78 MAPT (0.43) MAPTALOX15GAAFABP4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012008916-A1 FLAME RETARDANT AND INTUMESCENT COMPOUND AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-01-19 WO disclosed
US-7034187-B2 Poly(aralkyl ketone)s and methods of preparing the same AGENCY FOR SCIENCE, TECHNOLOGY, AND RESEARCH (SG) 2006-04-25 US disclosed
US-20050272905-A1 NOVEL POLY(ARALKYL KETONE)S AND METHODS OF PREPARING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2005-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050272905-A1 NOVEL POLY(ARALKYL KETONE)S AND METHODS OF PREPARING THE SAME ADSL, KHK, PKLR MAPT 3173/4885ALOX15 556/4885GAA 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.