Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767577 | 0.94 | MAPT (0.37) | KMT2ACYP3A4HSPD1HSPE1RAB9A | |
| SCHEMBL3899598 | 0.91 | ALDH1A1 (0.43) | KMT2ACYP3A4RAB9AMEN1MAPT | |
| SCHEMBL3895890 | 0.91 | KMT2A (0.41) | KMT2ACYP3A4MEN1MAPTMAOB | |
| SCHEMBL3891424 | 0.89 | PKM (0.38) | KMT2ACYP3A4HSPD1HSPE1RAB9A | |
| SCHEMBL3902581 | 0.88 | MAOB (0.47) | RAB9AMAPTMAOBCYP1B1MAOA | |
| SCHEMBL3890483 | 0.83 | MAPT (0.33) | KMT2ACYP3A4HSPD1HSPE1RAB9A | |
| SCHEMBL27840781 | 0.78 | KMT2A (0.42) | KMT2ACYP3A4HSPD1HSPE1RAB9A | |
| SCHEMBL3894990 | 0.78 | KMT2A (0.41) | KMT2ACYP3A4HSPD1HSPE1RAB9A | |
| SCHEMBL3894992 | 0.78 | KMT2A (0.41) | KMT2ACYP3A4HSPD1HSPE1RAB9A | |
| SCHEMBL27821478 | 0.75 | KMT2A (0.38) | KMT2ACYP3A4HSPD1HSPE1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099440-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | Seoul National University Industry Foundation (KR) | 2009-09-16 | — | — | EP | claimed |
| WO-2008069608-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | SEOUL NATIONALUNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-06-12 | — | — | WO | claimed |