Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767577 | 0.93 | MAPT (0.37) | ALDH1A1MAPTHPGDCYP3A4CYP1B1 | |
| SCHEMBL3897331 | 0.91 | KMT2A (0.41) | ALDH1A1MAPTCYP3A4CYP1B1RAB9A | |
| SCHEMBL3895890 | 0.90 | KMT2A (0.41) | MAPTCYP3A4CYP1B1SMN1; SMN2LMNA | |
| SCHEMBL3902581 | 0.87 | MAOB (0.47) | ALDH1A1MAPTCYP1B1NPC1RAB9A | |
| SCHEMBL3891424 | 0.84 | PKM (0.38) | ALDH1A1MAPTCYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL3890483 | 0.82 | MAPT (0.33) | ALDH1A1MAPTHPGDCYP3A4CYP1B1 | |
| SCHEMBL27869381 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCYP3A4CYP1B1 | |
| SCHEMBL5323475 | 0.72 | CYP1B1 (0.47) | ALDH1A1MAPTHPGDCYP3A4CYP1B1 | |
| SCHEMBL5324147 | 0.70 | MAPT (0.38) | ALDH1A1MAPTHPGDCYP3A4CYP1B1 | |
| SCHEMBL3899594 | 0.70 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDCYP3A4CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099440-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | Seoul National University Industry Foundation (KR) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008069608-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | SEOUL NATIONALUNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-06-12 | — | — | WO | disclosed |