⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368150 | 0.92 | MAPT (0.37) | — | |
| SCHEMBL29941222 | 0.90 | MAPT (0.35) | — | |
| SCHEMBL2795198 | 0.90 | MAPT (0.35) | — | |
| SCHEMBL9042088 | 0.90 | — | — | |
| SCHEMBL497532 | 0.90 | MAPT (0.38) | — | |
| SCHEMBL23661070 | 0.87 | MAPT (0.37) | — | |
| SCHEMBL29780367 | 0.87 | MAPT (0.37) | — | |
| SCHEMBL497034 | 0.87 | MAPT (0.37) | — | |
| SCHEMBL497686 | 0.87 | MAPT (0.37) | — | |
| SCHEMBL11814787 | 0.86 | MAPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376104-A1 | Bcl-2 Inhibitors | BEIGENE LTD. (KY) | 2024-11-14 | — | — | US | claimed |
| EP-3788042-A1 | BCL-2 INHIBITORS | BeiGene, Ltd. (KY) | 2021-03-10 | — | — | EP | claimed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | claimed |
| CN-110494433-A | Bruton's tyrosine kinase inhibitor | LIAO XIBIN | 2019-11-22 | — | — | CN | claimed |
| US-7521159-B2 | Multicolor electronic paper | XEROX CORPORATION (US) | 2009-04-21 | — | — | US | claimed |
| US-20060222973-A1 | Multicolor electronic paper | XEROX CORPORATION | 2006-10-05 | — | — | US | claimed |
| JP-2002543078-A | — | — | 2002-12-17 | — | — | JP | claimed |
| EP-1091959-A1 | NOVEL PYRROLO-(3,4-B)QUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICAMENT | MACEF (FR) | 2001-04-18 | — | — | EP | claimed |
| WO-2000064897-A1 | NOVEL PYRROLO-(3,4-B)QUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICAMENT | MACEF (FR) | 2000-11-02 | — | — | WO | claimed |
| EP-0172692-B1 | HEXAHYDROINDOLIZINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS AND INTERMEDIATES | McNeilab, Inc. (US) | 1990-04-18 | — | — | EP | claimed |
| EP-0172692-A1 | Hexahydroindolizine compounds, pharmaceutical compositions and methods and intermediates | McNeilab, Inc. (US) | 1986-02-26 | — | — | EP | claimed |
| US-4572911-A | ANTISECRETORY AND ANTIDEPRESSANT AGENTS | MCNEILAB, INC. (US) | 1986-02-25 | — | — | US | claimed |
| US-12516053-B2 | Bcl-2 inhibitors | BEONE MEDICINES I GMBH (CH) | 2026-01-06 | — | — | US | disclosed |
| EP-4545515-A1 | BCL-2 INHIBITORS | BeiGene Switzerland GmbH (CH) | 2025-04-30 | — | — | EP | disclosed |
| US-20240376104-A1 | Bcl-2 Inhibitors | BEIGENE LTD. (KY) | 2024-11-14 | — | — | US | disclosed |
| US-12077536-B2 | BCL-2 inhibitors | BEIGENE, LTD. (KY) | 2024-09-03 | — | — | US | disclosed |
| EP-0127048-A2 | Optically active diphenyl ether derivatives | BAYER AG (DE) | 1984-12-05 | — | — | EP | disclosed |
| EP-0041661-B1 | PREPARATION OF INTERMEDIATES OF CARBAPROSTACYCLINES | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-07-18 | — | — | EP | disclosed |
| EP-0062902-A1 | 2,3,4-Trinor-m-inter-phenylene-prostaglandin derivatives, their preparation and pharmaceutical compositions | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1982-10-20 | — | — | EP | disclosed |
| EP-0009658-B1 | PROCESS FOR THE PREPARATION OF OXALYL CHLORIDE | BAYER AG (DE) | 1981-08-26 | — | — | EP | disclosed |