SCHEMBL368150

SCHEMBL368150

C1=C2CCCCN2CCC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
ALDH1A1 P00352 1/20 0.37
USP2 O75604 1/20 0.32
INMT O95050 1/20 0.32
HPGD P15428 1/20 0.31
LMNA P02545 1/20 0.30
CHKA P35790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941222 0.98 MAPT (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL2795198 0.98 MAPT (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL497034 0.95 MAPT (0.37) MAPTALDH1A1USP2INMTHPGD
SCHEMBL6699994 0.93 ALDH1A1 (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL8420655 0.93 ALDH1A1 (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL23661069 0.93 ALDH1A1 (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL11110396 0.93 ALDH1A1 (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL497507 0.93 ALDH1A1 (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL23486255 0.93 ALDH1A1 (0.35) MAPTALDH1A1USP2INMTHPGD
SCHEMBL8992014 0.93 ALDH1A1 (0.35) MAPTALDH1A1USP2INMTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4716172-A 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates MCNEILAB, INC. (US) 1987-12-29 US claimed
EP-0241292-A2 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates McNeilab, Inc. (US) 1987-10-14 EP claimed
WO-2024034669-A1 SILANE COMPOUND ダイキン工業株式会社 2024-02-15 WO disclosed
WO-2023188842-A1 POLYETHER NITRILE FILM AND METHOD FOR PRODUCING POLYETHER NITRILE FILM 東レ株式会社 2023-10-05 WO disclosed
EP-3642284-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2020-04-29 EP disclosed
EP-3619274-A1 AQUEOUS DISPERSIONS OF ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2020-03-11 EP disclosed
US-10544166-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2020-01-28 US disclosed
WO-2019052660-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2019-03-21 WO disclosed
US-20180186817-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2018-07-05 US disclosed
EP-3259300-A1 METHOD FOR PRODUCING POLYCARBONATES BY TRANSESTERIFICATION OF DITHIOCARBONATES OR THE SELENIUM ANALOGUES THEREOF WITH BISPHENOLS Covestro Deutschland AG (DE) 2017-12-27 EP disclosed
CN-103649084-B 1,4 disubstituted 1,2,3 triazoles, methods for making them and its diagnostic and therapeutic use 国家科学研究中心 2017-03-29 CN disclosed
EP-0431605-A2 1-Azabicyclo[m.n.O]alkane derivatives, their salts and process for preparing them SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1991-06-12 EP disclosed
US-4916223-A ALPAH 2-ADRENOCEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1990-04-10 US disclosed
US-4831035-A Substituted hexahydroarylquinolizines MERCK & CO., INC. (US) 1989-05-16 US disclosed
EP-0259092-A1 Substituted hexahydroarylquinolizines MERCK & CO. INC. (US) 1988-03-09 EP disclosed
US-4716172-A 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates MCNEILAB, INC. (US) 1987-12-29 US disclosed
US-4716172-A 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates MCNEILAB, INC. (US) 1987-12-29 US disclosed
US-4716172-A 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates MCNEILAB, INC. (US) 1987-12-29 US disclosed
EP-0241292-A2 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates McNeilab, Inc. (US) 1987-10-14 EP disclosed
EP-0241292-A2 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates McNeilab, Inc. (US) 1987-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180186817-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME BLVRB, CDYL, CRY1 MAPT 277/4885ALDH1A1 836/4885USP2 972/4885
US-10544166-B2 Compound and color conversion film comprising same BLVRB, CDYL, CRY1 MAPT 277/4885ALDH1A1 836/4885USP2 972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.