SCHEMBL497686

SCHEMBL497686

C1=C(N2CCCCC2)CCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.37
ALDH1A1 P00352 6/20 0.37
LMNA P02545 4/20 0.33
HTT P42858 6/20 0.32
USP2 O75604 4/20 0.32
NPC1 O15118 4/20 0.32
MEN1 O00255 3/20 0.32
POLB P06746 3/20 0.32
RECQL P46063 3/20 0.32
KMT2A Q03164 3/20 0.32
RAB9A P51151 3/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 2/20 0.32
INMT O95050 1/20 0.32
TP53 P04637 1/20 0.32
GAA P10253 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23661070 1.00 MAPT (0.37) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL497532 0.97 MAPT (0.38) MAPTALDH1A1LMNAHPGDCHKA
SCHEMBL497507 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL8420655 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL8992014 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL23661069 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL6699994 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL23486255 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL11110396 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2
SCHEMBL14818806 0.93 ALDH1A1 (0.35) MAPTALDH1A1LMNAHTTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098640-A1 PREPARATION METHOD FOR DRUG INTERMEDIATE 浙江华海药业股份有限公司 2023-06-08 WO disclosed
US-20210221776-A1 PERFLUOROAMINOOLEFINS AND METHODS OF MAKING AND USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2021-07-22 US disclosed
WO-2021012671-A1 HIGHLY EFFICIENT PREPARATION METHOD FOR PROGESTERONE WITH LOW POLLUTION 浙江神洲药业有限公司 2021-01-28 WO disclosed
WO-2013177708-A1 BORENIUM FRUSTRATED LEWIS PAIR CATALYSTS STEPHAN CONSULTING CORPORATION (CA) 2013-12-05 WO disclosed
CN-102224105-B Method for preparing ssz-26/33 zeolites using novel structure directing agents CHEVRON USA INC 2013-09-04 CN disclosed
CN-101827814-B Novel carbamoylglycine derivatives DSM IP ASSETS BV 2012-11-28 CN disclosed
US-8198501-B2 Zeolite catalyst for hydroisomerization of light paraffins to produce high octane gasoline CHEVRON U.S.A. INC. (US) 2012-06-12 US disclosed
US-8119621-B2 Tetrahydro-cyclopentyl pyrazole cannabinoid modulators JANSSEN PHARMACEUTICA N.V. (BE) 2012-02-21 US disclosed
US-8119621-B2 Tetrahydro-cyclopentyl pyrazole cannabinoid modulators JANSSEN PHARMACEUTICA N.V. (BE) 2012-02-21 US disclosed
US-8119621-B2 Tetrahydro-cyclopentyl pyrazole cannabinoid modulators JANSSEN PHARMACEUTICA N.V. (BE) 2012-02-21 US disclosed
US-20070054837-A1 Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor INTERNATIONAL FLAVORS & FRAGRANCES INC. 2007-03-08 US disclosed
US-7169747-B2 Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2007-01-30 US disclosed
US-7169747-B2 Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2007-01-30 US disclosed
US-4221800-A ANTIALLERGENS, ANTIHISTAMINES MILES LABORATORIES, INC. (US) 1980-09-09 US disclosed
US-3991111-A ANTIBIOTICS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-11-09 US disclosed
US-3979455-A Preparation of dioxyimino-cycloalkanones and related intermediates TEXACO INC. (US) 1976-09-07 US disclosed
US-3951962-A ANTIBACTERIAL YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-20 US disclosed
US-3948907-A VINYL POLYMERIZATION INITIATORS THE DOW CHEMICAL COMPANY (US) 1976-04-06 US disclosed
US-3948891-A INITIATORS OF VINYL POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1976-04-06 US disclosed
US-3947418-A POLYMERIZATION INITIATORS THE DOW CHEMICAL COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210221776-A1 PERFLUOROAMINOOLEFINS AND METHODS OF MAKING AND USING THE SAME FGB, RFTN1, AFF1 MAPT 3083/4885ALDH1A1 4051/4885LMNA 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.