Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894228 | 1.00 | GABRR1 (0.41) | GABRR1GABBR1 | |
| SCHEMBL3894222 | 1.00 | GABRR1 (0.41) | GABRR1GABBR1 | |
| SCHEMBL3892896 | 0.81 | GABRR1 (0.43) | GABRR1GABBR1 | |
| SCHEMBL3895253 | 0.78 | GABRR1 (0.36) | GABRR1GABBR1 | |
| SCHEMBL3894153 | 0.78 | GABRR1 (0.36) | GABRR1GABBR1 | |
| SCHEMBL6314582 | 0.73 | — | — | |
| SCHEMBL4252850 | 0.69 | — | — | |
| SCHEMBL3892266 | 0.65 | OAT (0.35) | — | |
| SCHEMBL3892898 | 0.63 | GABBR1 (0.41) | GABRR1GABBR1 | |
| SCHEMBL3894147 | 0.61 | GABBR1 (0.36) | GABRR1GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773740-B1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | UNIV SYDNEY (AU) | 2009-02-18 | — | — | EP | disclosed |
| US-20080032950-A1 | Neurologically-Active Compounds | THE UNIVERSITY OF SYDNEY (AU) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032950-A1 | Neurologically-Active Compounds | GABRE, GABRA5, GABRA1 | GABRR1 14/4885GABBR1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.