Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.64 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25007822 | 0.84 | CA12 (0.66) | CA12CA1CA2CA9CA14 | |
| SCHEMBL23812256 | 0.84 | CA12 (0.66) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27568135 | 0.83 | ALDH1A1 (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL109451 | 0.82 | CA1 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL948406 | 0.82 | CA2 (0.90) | CA12CA1CA2CA9CA14 | |
| SCHEMBL118882 | 0.79 | CA1 (0.61) | CA12CA1CA2CA9CA14 | |
| Hydrazine SCHEMBL10771056 | 0.78 | CA12 (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6592668 | 0.78 | CA12 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL20390885 | 0.77 | CA1 (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18554570 | 0.77 | ALDH1A1 (0.43) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |