⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064189 | 1.00 | — | — | |
| SCHEMBL4676923 | 1.00 | — | — | |
| SCHEMBL17142633 | 0.87 | ALDH1A1 (0.47) | — | |
| SCHEMBL721962 | 0.87 | ALDH1A1 (0.47) | — | |
| SCHEMBL17148081 | 0.87 | ALDH1A1 (0.47) | — | |
| SCHEMBL2674136 | 0.87 | PDCD1 (0.44) | — | |
| SCHEMBL12279922 | 0.87 | PDCD1 (0.44) | — | |
| SCHEMBL12280022 | 0.87 | PDCD1 (0.44) | — | |
| SCHEMBL722623 | 0.86 | ALOX15 (0.57) | — | |
| SCHEMBL28960037 | 0.85 | PDCD1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204028-B | tetrahydro-1H-pyrazino [2,1-a ] isoindoloquinoline compounds for use in the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | claimed |
| EP-3802539-B1 | TETRAHYDRO-1H-PYRAZINO[2,1-A]ISOINDOLYLQUINOLINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN LA ROCHE (CH) | 2023-09-20 | — | — | EP | claimed |
| CN-113493628-B | Quantum dot ink and preparation method of quantum dot film | TCL科技集团股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-110437463-B | Dendritic polymer, preparation method and application thereof | 威海晨源分子新材料有限公司 | 2022-01-21 | — | — | CN | claimed |
| CN-113493628-A | Quantum dot ink and preparation method of quantum dot film | TCL科技集团股份有限公司 | 2021-10-12 | — | — | CN | claimed |
| CN-113122053-A | Quantum dot ink and preparation method of quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-112204028-A | tetrahydro-1H-pyrazino [2,1-a ] isoindolyl quinoline compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-106366310-B | Carboxyl-containing high-refractive-index hyperbranched polyesteramide, preparation method thereof and application thereof in plastic modification | 威海晨源分子新材料有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-110437463-A | Dendritic, preparation method and its application | WEIHAI CY DENDRIMER TECH CO LTD | 2019-11-12 | — | — | CN | claimed |
| CN-106366310-A | Carboxyl-containing high-refractive-index hyperbranched polyesteramide and preparation method thereof, as well as application of carboxyl-containing high-refractive-index hyperbranched polyesteramide to plastic modification | 威海晨源分子新材料有限公司 | 2017-02-01 | — | — | CN | claimed |
| EP-4583883-A2 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACID-BASED THERAPEUTICS AND METHODS THEREOF | Nanotech Pharma Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| EP-4211116-B1 | NOVEL HETEROCYCLIC ANTIBIOTICS | HOFFMANN LA ROCHE (CH) | 2024-08-07 | — | — | EP | disclosed |
| US-20240208960-A1 | AMINOTHIAZOLE COMPOUNDS AS C-KIT INHIBITORS | TAKEDA PHARMACEUTICALS U.S.A., INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208960-A1 | AMINOTHIAZOLE COMPOUNDS AS C-KIT INHIBITORS | TAKEDA PHARMACEUTICALS U.S.A., INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240109917-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2024-04-04 | — | — | US | disclosed |
| EP-1701939-A1 | ANTHRAQUINONE COMPOUNDS AS ANTI CANCER COMPOUNDS | Somanta Limited (GB) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005061453-A1 | ANTHARQUINONE COMPOUNDS AS ANTI CANCER COMPOUNDS | SOMANTA LIMITED (GB) | 2005-07-07 | — | — | WO | disclosed |
| EP-1453501-A1 | N- ARYL-N'-ARYLCYCLOALKYL-UREA DERIVATIVES AS MCH ANTAGONISTS FOR THE TREATMENT OF OBESITY | SCHERING CORPORATION (US) | 2004-09-08 | — | — | EP | disclosed |
| US-20040122017-A1 | MCH antagonists for the treatment of obesity | SCHERING CORPORATION | 2004-06-24 | — | — | US | disclosed |
| WO-2003047568-A1 | N-ARYL-N'-ARYLCYCLOALKYL-UREA DERIVATIVES AS MCH ANTAGONISTS FOR THE TREATMENT OF OBESITY | SCHERING CORPORATION (US) | 2003-06-12 | — | — | WO | disclosed |