SCHEMBL721962

SCHEMBL721962

NCCN1CCCC(O)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HTR1A P08908 1/20 0.43
KDM4E B2RXH2 5/20 0.42
ALOX15 P16050 1/20 0.42
POLB P06746 2/20 0.41
TSHR P16473 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HRH2 P25021 1/20 0.40
HRH1 P35367 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
HTT P42858 3/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
GAA P10253 1/20 0.37
XBP1 P17861 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17142633 1.00 ALDH1A1 (0.47) ALDH1A1HTR1AKDM4EALOX15POLB
SCHEMBL17148081 1.00 ALDH1A1 (0.47) ALDH1A1HTR1AKDM4EALOX15POLB
SCHEMBL17142474 0.88 HTR1A (0.48) ALDH1A1HTR1AKDM4EPOLBTSHR
SCHEMBL3899323 0.87
SCHEMBL10064189 0.87
SCHEMBL4676923 0.87
SCHEMBL3087289 0.86 HTR1A (0.47) ALDH1A1HTR1AKDM4EPOLBTSHR
SCHEMBL29714780 0.83
SCHEMBL12193442 0.81 ALDH1A1 (0.49) ALDH1A1HTR1AKDM4EPOLBTSHR
SCHEMBL12193444 0.81 ALDH1A1 (0.49) ALDH1A1HTR1AKDM4EPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122050-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
US-20260027090-A1 Methods of Inhibiting Osteoclastogenesis and Osteoclast Activity VTV THERAPEUTICS LLC (US) 2026-01-29 US disclosed
US-12091407-B2 Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof VTV THERAPEUTICS LLC (US) 2024-09-17 US disclosed
US-20240109917-A1 PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS ACTELION PHARMACEUTICALS LTD (CH) 2024-04-04 US disclosed
EP-4267585-A1 PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS Actelion Pharmaceuticals Ltd (CH) 2023-11-01 EP disclosed
US-20230312548-A1 SUBSTITUTE FUSED IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF VTV THERAPEUTICS LLC 2023-10-05 US disclosed
CN-116802184-A Pyrazolothiazole carboxamides and their use as PDGFR inhibitors 埃科特莱茵药品有限公司 2023-09-22 CN disclosed
US-20230250094-A1 SMALL MOLECULE INHIBITORS OF TDP-43 ACTIVITY AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2023-08-10 US disclosed
US-20230250094-A1 SMALL MOLECULE INHIBITORS OF TDP-43 ACTIVITY AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2023-08-10 US disclosed
US-20230250094-A1 SMALL MOLECULE INHIBITORS OF TDP-43 ACTIVITY AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2023-08-10 US disclosed
US-7557215-B2 Anthraquinone compounds as anti cancer compounds SOMANTA LIMITED (GB) 2009-07-07 US disclosed
EP-1701939-B1 ANTHRAQUINONE COMPOUNDS AS ANTI CANCER COMPOUNDS SOMANTA LTD (GB) 2009-02-25 EP disclosed
WO-2008062252-A1 N-OXIDES OF CYTOTOXIC ANTHRAQUINONES AS HYPOXIA-TARGETING PRODRUGS IN CANCER TREATMENT ACCESS PHARMACEUTICALS, INC (US) 2008-05-29 WO disclosed
US-20080027107-A1 Antharquinone Compounds as Anti Cancer Compounds SOMANTA LIMITED (GB) 2008-01-31 US disclosed
EP-1858836-A1 ANALOGUES OF THE AZINOMYCINS AS ANTI-TUMOUR AGENTS AND AS PRODRUGS SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) 2007-11-28 EP disclosed
WO-2007129195-A2 4-PYRIMIDINE-5-AMINO-PYRAZOLE COMPOUNDS PFIZER PRODUCTS INC. (US) 2007-11-15 WO disclosed
CN-1934079-A Anthraquinone compounds as anti cancer compounds SOMANTA LTD (GB) 2007-03-21 CN disclosed
WO-2006097730-A1 ANALOGUES OF THE AZINOMYCINS AS ANTI-TUMOUR AGENTS AND AS PRODRUGS SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) 2006-09-21 WO disclosed
EP-1701939-A1 ANTHRAQUINONE COMPOUNDS AS ANTI CANCER COMPOUNDS Somanta Limited (GB) 2006-09-20 EP disclosed
WO-2005061453-A1 ANTHARQUINONE COMPOUNDS AS ANTI CANCER COMPOUNDS SOMANTA LIMITED (GB) 2005-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027107-A1 Antharquinone Compounds as Anti Cancer Compounds TOP2A, TOP2B, RECQL ALDH1A1 1484/4885HTR1A 1615/4885KDM4E 1024/4885
US-12091407-B2 Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof GLS, HMOX2, REN ALDH1A1 1872/4885HTR1A 2625/4885KDM4E 2451/4885
US-20230250094-A1 SMALL MOLECULE INHIBITORS OF TDP-43 ACTIVITY AND USES THEREOF TARDBP, TDP1, TDP2 ALDH1A1 2936/4885HTR1A 659/4885KDM4E 2791/4885
US-20230312548-A1 SUBSTITUTE FUSED IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF GLS, HMOX2, REN ALDH1A1 1697/4885HTR1A 2693/4885KDM4E 2332/4885
US-20260027090-A1 Methods of Inhibiting Osteoclastogenesis and Osteoclast Activity CSF1R, CD209, NFATC1 ALDH1A1 3818/4885HTR1A 3902/4885KDM4E 276/4885
US-20240109917-A1 PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS PDGFRA, PDGFRB, ABL1 ALDH1A1 916/4885HTR1A 727/4885KDM4E 2700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.