Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900652 | 0.90 | RAB9A (0.46) | NPC1CDK1SIGMAR1TMEM97RAB9A | |
| SCHEMBL3906076 | 0.81 | POLB (0.56) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3899503 | 0.79 | NPC1 (0.53) | NPC1CDK1SIGMAR1TMEM97RAB9A | |
| SCHEMBL3896082 | 0.79 | MMP3 (0.44) | NPC1RAB9AGAAMCHR1SMN1; SMN2 | |
| SCHEMBL3900423 | 0.78 | F10 (0.43) | CDK1SIGMAR1TMEM97 | |
| SCHEMBL4684512 | 0.76 | CA12 (0.47) | — | |
| SCHEMBL3900527 | 0.76 | CDK1 (0.36) | CDK1EGLN1ALDH1A1 | |
| SCHEMBL3896153 | 0.74 | F2 (0.46) | NPC1CDK1SIGMAR1TMEM97RAB9A | |
| SCHEMBL3897950 | 0.73 | GPR119 (0.56) | — | |
| SCHEMBL6874766 | 0.73 | CA12 (0.48) | GAAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |