Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899503 | 0.84 | NPC1 (0.53) | RAB9AMEN1KMT2ANPC1MCHR1 | |
| SCHEMBL3900652 | 0.83 | RAB9A (0.46) | F10RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3897181 | 0.77 | F10 (0.60) | F10RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL27001729 | 0.76 | CYP19A1 (0.41) | — | |
| SCHEMBL7566194 | 0.76 | NPC1 (0.75) | F10RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3900535 | 0.74 | NPC1 (0.43) | RAB9ANPC1MCHR1HSP90AA1TRPA1 | |
| SCHEMBL3902858 | 0.73 | RAB9A (0.58) | F10RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL5175835 | 0.72 | EPHX2 (0.43) | F10RAB9AKMT2AMCHR1TRPA1 | |
| SCHEMBL5536198 | 0.71 | NAMPT (0.64) | RAB9AMEN1KMT2ANPC1EPHX2 | |
| SCHEMBL5405545 | 0.70 | TRPV4 (0.54) | MEN1KMT2AHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |