Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25735703 | 0.84 | NR1I2 (0.54) | KMT2AALDH1A1HSD11B1MAPK1MEN1 | |
| SCHEMBL11482764 | 0.83 | KMT2A (0.53) | KMT2AALDH1A1HSD11B1POLBMAPK1 | |
| SCHEMBL25736043 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1HSD11B1MAPTLMNA | |
| SCHEMBL3899893 | 0.80 | KMT2A (0.56) | KMT2AHSD11B1MAPK1MAPT | |
| SCHEMBL25735706 | 0.80 | KMT2A (0.56) | KMT2AHSD11B1MAPK1MEN1MAPT | |
| SCHEMBL29385732 | 0.79 | PTGS2 (0.57) | TP53MAPTLMNA | |
| SCHEMBL27709189 | 0.78 | MAPK1 (0.56) | KMT2AALDH1A1HSD11B1POLBTP53 | |
| SCHEMBL30309104 | 0.78 | POLB (0.47) | KMT2AALDH1A1HSD11B1POLBTP53 | |
| SCHEMBL25702587 | 0.78 | KMT2A (0.53) | KMT2AHSD11B1MAPK1MEN1MAPT | |
| SCHEMBL28210787 | 0.77 | ALDH1A1 (0.48) | KMT2AALDH1A1HSD11B1POLBTEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1788429-B1 | Method of making a lithographic printing plate | AGFA GRAPHICS NV (BE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007057346-A2 | METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2007-05-24 | — | — | WO | disclosed |
| EP-1788429-A1 | Method of making a lithographic printing plate | Agfa Graphics N.V. (BE) | 2007-05-23 | — | — | EP | disclosed |