Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GPR3 | P46089 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31313485 | 0.74 | GPR3 (0.48) | KMT2AGPR3KDM4EHSD17B10MAPT | |
| SCHEMBL20855328 | 0.74 | GPR3 (0.48) | KMT2AGPR3KDM4EHSD17B10MAPT | |
| SCHEMBL20855331 | 0.74 | GPR3 (0.54) | KMT2AGPR3KDM4EHSD17B10MAPT | |
| SCHEMBL30277502 | 0.74 | GPR3 (0.54) | KMT2AGPR3KDM4EHSD17B10MAPT | |
| SCHEMBL12533983 | 0.72 | GPR3 (0.47) | KMT2AGPR3KDM4EMEN1ALDH1A1 | |
| SCHEMBL16414501 | 0.71 | GPR3 (0.50) | KMT2AGPR3KDM4EHSD17B10MAPT | |
| SCHEMBL10641955 | 0.68 | LMNA (0.57) | KMT2AKDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL29099813 | 0.67 | GPR3 (0.42) | KMT2AGPR3KDM4EMAPTMEN1 | |
| SCHEMBL1386112 | 0.66 | GPR3 (0.54) | KMT2AGPR3KDM4EHSD17B10MAPT | |
| SCHEMBL7607540 | 0.66 | GPR3 (0.54) | KMT2AGPR3KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916658-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-0322926-B2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0322926-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0916658-A1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | Nichols Institute Diagnostics (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5290936-A | Indicators or labels for antibodies or medical diagnosis | LONDON DIAGNOSTICS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| WO-1989006231-A1 | ASSAYS UTILIZING IMPROVED CHEMILUMINESCENT ESTERS, THIOESTERS AND AMIDES | LONDON DIAGNOSTICS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0322926-A2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | LONDON DIAGNOSTICS, INC. (US) | 1989-07-05 | — | — | EP | disclosed |