SCHEMBL7607540

SCHEMBL7607540

Oc1nc2ccccc2c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.54
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 6/20 0.46
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
MAOA P21397 2/20 0.46
GLA P06280 2/20 0.46
HPGD P15428 2/20 0.46
CASP1 P29466 2/20 0.46
CASP7 P55210 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46
NQO2 P16083 1/20 0.46
DRD1 P21728 1/20 0.46
ACHE P22303 1/20 0.46
SLC6A2 P23975 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14865253 0.81 GPR3 (0.41) GPR3KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL3503005 0.80 KMT2A (0.45) GPR3KMT2AALDH1A1ACHEHTT
SCHEMBL12480311 0.80 KMT2A (0.41) GPR3KMT2AKDM4EALDH1A1GLA
SCHEMBL28605609 0.79 KDM4E (0.44) KMT2AKDM4EALDH1A1MAOAHPGD
SCHEMBL311283 0.78 KDM4E (0.44) GPR3KMT2AKDM4EALDH1A1HSD17B10
Benzoylenurea SCHEMBL1752723 0.78 KDM4E (0.45) GPR3KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL851828 0.78 KDM4E (0.44) GPR3KMT2AKDM4EALDH1A1HSD17B10
Benzoylenurea SCHEMBL29460047 0.78 KDM4E (0.45) GPR3KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL12480194 0.78 KDM4E (0.43) KMT2AKDM4EGLACASP1CASP7
SCHEMBL3503833 0.78 MPO (0.40) KMT2ANQO2ACHEHTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1254243-C Pharmaceutical compositions comprising chelidonine or derivatives thereof EUN JAE SOON (KR) 2006-05-03 CN claimed
CN-1516583-A Pharmaceutical compositions comprising chelidonine or derivatives thereof ���ش����������޹�˾ 2004-07-28 CN claimed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US claimed
WO-2021073603-A1 BENZOPHENANTHRIDINE ALKALOIDS AND THEIR METHODS OF USE Chengdu Anticancer Bioscience, Ltd. (CN) 2021-04-22 WO disclosed
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS THE SCRIPPS RESEARCH INSTITUTE 2020-10-08 US disclosed
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-24 US disclosed
WO-2017011531-A2 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-01-19 WO disclosed
CN-103380132-B phenanthridine macrocyclic hepatitis C serine protease inhibitors 益安药业 2016-08-31 CN disclosed
CN-101754974-B As the macrocylc compound of antiviral agent MSD ITALIA S.R.L. (IT) 2016-02-03 CN disclosed
WO-2015175678-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-11-19 WO disclosed
CN-103380132-A Phenanthridine macrocyclic hepatitis c serine protease inhibitors ENATA PHARMACEUTICALS INC 2013-10-30 CN disclosed
EP-1265485-A1 USE OF PIPERIDINE BENZODERIVATIVES AS FUNGICIDES Leis, Michelangelo (IT) 2002-12-18 EP disclosed
WO-2001062089-A1 USE OF PIPERIDINE BENZODERIVATIVES AS FUNGICIDES LEIS MICHELANGELO (IT) 2001-08-30 WO disclosed
CN-1050604-C Compound with antipsychotic effect MEIJI SEIKA KABUSHIKA KAISHA (JP) 2000-03-22 CN disclosed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US disclosed
CN-1164856-A Novel alkylamino derivatives as sigma 2 selective ligands MITSUBISHI CHEM CORP (JP) 1997-11-12 CN disclosed
US-5599815-A SIDE EFFECT REDUCTION MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-02-04 US disclosed
CN-1103534-A Compound with antipsychotic effect MEIJI SEIKA CO (JP) 1995-06-07 CN disclosed
EP-0635506-A1 COMPOUND WITH ANTIPSYCHOTIC EFFECT MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-01-25 EP disclosed
EP-0380264-A2 Halogenation process DowElanco (US) 1990-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS ALDH1A2, DDT, CLTB GPR3 2506/4885KMT2A 2223/4885KDM4E 3074/4885
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS CYBA, DDT, DRD1 GPR3 2975/4885KMT2A 1916/4885KDM4E 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.