Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.64 |
| ▸ | NPC1 | O15118 | 12/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | AGER | Q15109 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299674 | 0.87 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2MAPTBRD4 | |
| SCHEMBL14018616 | 0.84 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTBRD4 | |
| SCHEMBL3892750 | 0.84 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2MAPTPPARG | |
| SCHEMBL1119373 | 0.84 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2MAPTPPARG | |
| SCHEMBL3891438 | 0.82 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2MAPTBRD4 | |
| SCHEMBL4297483 | 0.81 | ADORA2A (0.62) | RAB9ANPC1SMN1; SMN2MAPTBRD4 | |
| SCHEMBL3190864 | 0.80 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2MAPTPPARG | |
| SCHEMBL4292558 | 0.79 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTPPARG | |
| SCHEMBL12124359 | 0.79 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2MAPTBRD4 | |
| SCHEMBL3223685 | 0.78 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | claimed |
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | disclosed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | disclosed |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | RAB9A 764/4885NPC1 1408/4885SMN1; SMN2 1476/4885 |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | RAB9A 1174/4885NPC1 1513/4885SMN1; SMN2 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.