Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395753 | 0.85 | GRIN1 (0.41) | GRIN1GRIN2B | |
| SCHEMBL10976001 | 0.84 | GRIN1 (0.37) | GRIN1GRIN2B | |
| SCHEMBL1594054 | 0.84 | PKM (0.34) | SIRT2 | |
| SCHEMBL3394435 | 0.82 | ICMT (0.32) | GRIN1GRIN2B | |
| SCHEMBL11243462 | 0.82 | CHRNA1 (0.34) | GRIN1GRIN2B | |
| SCHEMBL11248890 | 0.82 | ABCB11 (0.37) | GRIN1GRIN2B | |
| SCHEMBL11231723 | 0.80 | GRIN1 (0.37) | GRIN1GRIN2B | |
| SCHEMBL28604606 | 0.79 | TAAR1 (0.39) | TAAR1 | |
| SCHEMBL11244135 | 0.78 | GRIN1 (0.44) | GRIN1GRIN2B | |
| SCHEMBL11241229 | 0.76 | CHRNA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |