Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907879 | 0.81 | CYP1A2 (0.37) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3902761 | 0.80 | PTGS2 (0.43) | ALDH1A1GABRA1GABRG2GABRB3CHRNB2 | |
| SCHEMBL6718297 | 0.73 | SLC6A4 (0.40) | KDM4EALDH1A1MAPTMAPK1TSHR | |
| SCHEMBL14355174 | 0.73 | SIGMAR1 (0.37) | KDM4EL3MBTL1SLC6A3BCHEACHE | |
| SCHEMBL31330199 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL69345 | 0.71 | TNF (0.61) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL27988223 | 0.71 | TNF (0.61) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| Biphenyl SCHEMBL1073325 | 0.71 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL29399206 | 0.71 | TNF (0.61) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL29156136 | 0.69 | TNF (0.59) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550546-B2 | Norbornene-based polymers, films, polarizing plates and liquid crystal display devices | FUJIFILM CORPORATION (JP) | 2009-06-23 | — | — | US | disclosed |
| US-20080033133-A1 | NORBORNENE-BASED POLYMERS, FILMS, POLARIZING PLATES AND LIQUID CRYSTAL DISPLAY DEVICES | FUJIFILM CORPORATION (JP) | 2008-02-07 | — | — | US | disclosed |