SCHEMBL3900855

SCHEMBL3900855

CCCCCC(CN(O)C=O)C(=O)NS(=O)(=O)CCCC

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 7/20 0.45
MMP12 P39900 1/20 0.41
PDF Q9HBH1 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3901552 0.86 BMP1 (0.49) BMP1MMP12PDF
SCHEMBL3903238 0.84 BMP1 (0.45) BMP1MMP12
SCHEMBL3901199 0.83 BMP1 (0.48) BMP1MMP12
SCHEMBL1597847 0.79 CA1 (0.54) BMP1MMP12PDF
SCHEMBL1597846 0.79 CA1 (0.54) BMP1MMP12PDF
SCHEMBL1597844 0.79 CA1 (0.54) BMP1MMP12PDF
SCHEMBL3900004 0.78 BMP1 (0.55) BMP1MMP12
SCHEMBL5476347 0.78 BMP1 (0.48) BMP1MMP12PDF
SCHEMBL3895773 0.77 ALDH1A1 (0.47) BMP1MMP12
SCHEMBL4059513 0.77 BMP1 (0.47) BMP1MMP12PDF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1615629-B1 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2009-03-18 EP claimed
EP-1615629-A4 PEPTIDE DEFORMYLASE INHIBITORS CHRISTENSEN SIEGFRIED B IV (US) 2007-02-28 EP disclosed
EP-1615629-A1 PEPTIDE DEFORMYLASE INHIBITORS Christensen, Siegfried B. IV (US) 2006-01-18 EP disclosed
WO-2004098584-A1 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2004-11-18 WO disclosed