Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 7/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900855 | 0.83 | BMP1 (0.45) | BMP1MMP12 | |
| SCHEMBL3900001 | 0.81 | ALDH1A1 (0.47) | BMP1CYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL3898472 | 0.78 | BMP1 (0.51) | BMP1 | |
| SCHEMBL3900004 | 0.77 | BMP1 (0.55) | BMP1MMP12 | |
| SCHEMBL6024214 | 0.77 | HDAC1 (0.44) | BMP1CYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL3911104 | 0.74 | BMP1 (0.56) | BMP1MMP12MMP2 | |
| SCHEMBL6024256 | 0.73 | ALDH1A1 (0.52) | BMP1HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1595891 | 0.73 | BMP1 (0.57) | BMP1MMP12 | |
| SCHEMBL1595893 | 0.73 | BMP1 (0.57) | BMP1MMP12 | |
| SCHEMBL1595896 | 0.73 | BMP1 (0.57) | BMP1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615629-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-03-18 | — | — | EP | claimed |