Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482772 | 0.80 | RAB9A (0.45) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3903167 | 0.78 | OPRM1 (0.44) | LMNACASROPRM1CYP3A4OPRL1 | |
| SCHEMBL3911825 | 0.78 | CNR1 (0.50) | LMNAALDH1A1CASROPRM1OPRK1 | |
| SCHEMBL3908089 | 0.77 | CASR (0.53) | RAB9ANPC1SMN1; SMN2CASROPRL1 | |
| SCHEMBL3916716 | 0.77 | CASR (0.53) | LMNASMN1; SMN2ALDH1A1CASROPRM1 | |
| SCHEMBL3905862 | 0.76 | CYP2C19 (0.51) | RAB9ALMNASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL3907315 | 0.76 | GAA (0.43) | LMNASMN1; SMN2CASROPRM1OPRL1 | |
| SCHEMBL3903074 | 0.75 | CASR (0.50) | RAB9ANPC1CASROPRM1OPRL1 | |
| SCHEMBL3906098 | 0.75 | OPRL1 (0.56) | CASROPRM1OPRL1 | |
| SCHEMBL3282858 | 0.74 | CCR3 (0.50) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | claimed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |