Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743063 | 0.84 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL390165 | 0.81 | KDM4E (0.60) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL2801067 | 0.80 | FDPS (0.57) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL10614204 | 0.78 | KDM4E (0.51) | TAS1R3TAS1R1TAS1R2PREPKDM4E | |
| SCHEMBL10614856 | 0.78 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2JAK2TYK2 | |
| SCHEMBL1544471 | 0.77 | KDM4E (0.55) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL6504213 | 0.77 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2BRAFSMARCA2 | |
| SCHEMBL7271571 | 0.77 | ALDH1A1 (0.57) | JAK2TYK2KDM4EALDH1A1 | |
| SCHEMBL13701663 | 0.77 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 | |
| SCHEMBL13702388 | 0.77 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2229163-A | — | — | None | — | — | JP | disclosed |
| JP-H02229163-A | N-(2-CHLOROISONICOTINOYL)DERIVATIVE OR FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL PURPOSES CONTAINING THE SAME | NIPPON KAYAKU CO LTD | 1990-09-11 | — | — | JP | disclosed |