Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 9/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3897929 | 0.81 | F10 (0.44) | F10F2TMPRSS6PTPN1PTPN22 | |
| SCHEMBL14132055 | 0.78 | F10 (0.45) | F10PTPN1PTPN22 | |
| SCHEMBL3912355 | 0.76 | KLK7 (0.61) | KLK7TLR2TLR1BCL2PTPN1 | |
| SCHEMBL29401167 | 0.76 | KLK7 (0.61) | KLK7TLR2TLR1BCL2PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3901330 | 0.71 | F10 (0.52) | F10F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL3909089 | 0.71 | F10 (0.52) | F10F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL3901258 | 0.70 | F10 (0.59) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL3900546 | 0.70 | F10 (0.45) | F10F2TMPRSS6 | |
| SCHEMBL29398857 | 0.70 | KLK7 (0.53) | KLK7TLR2TLR1BCL2 | |
| SCHEMBL7441367 | 0.69 | KLK7 (0.53) | KLK7TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |