Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.63 |
| ▸ | DRD4 | P21917 | 18/20 | 0.63 |
| ▸ | DRD3 | P35462 | 15/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349978 | 0.93 | DRD2 (0.65) | DRD2DRD4DRD3L3MBTL1 | |
| Toluene SCHEMBL3905671 | 0.87 | KDM4E (0.46) | DRD2DRD4DRD3L3MBTL1 | |
| Toluene SCHEMBL3903622 | 0.84 | KDM4E (0.44) | DRD2DRD4DRD3 | |
| Toluene SCHEMBL3904509 | 0.82 | REN (0.47) | DRD2DRD4DRD3 | |
| Toluene SCHEMBL3910413 | 0.80 | REN (0.55) | DRD2DRD4DRD3 | |
| Toluene SCHEMBL3916407 | 0.80 | REN (0.51) | — | |
| Toluene SCHEMBL3904976 | 0.79 | REN (0.53) | — | |
| Hydrochloric Acid SCHEMBL8055383 | 0.77 | DRD2 (0.97) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8054953 | 0.77 | DRD2 (0.97) | DRD2DRD4DRD3 | |
| Toluene SCHEMBL3909886 | 0.75 | CHRM2 (0.54) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |