Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL3901994 | 0.87 | DRD2 (0.63) | DRD2DRD4DRD3L3MBTL1 | |
| Toluene SCHEMBL3903622 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1MEN1KMT2ADRD2 | |
| Toluene SCHEMBL3904509 | 0.85 | REN (0.47) | KDM4EALDH1A1MEN1KMT2ADRD2 | |
| Toluene SCHEMBL3916407 | 0.82 | REN (0.51) | MEN1KMT2ARENNPC1 | |
| Toluene SCHEMBL3910413 | 0.82 | REN (0.55) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| Toluene SCHEMBL3904976 | 0.81 | REN (0.53) | MEN1KMT2AREN | |
| Toluene SCHEMBL3916489 | 0.80 | CHRM2 (0.51) | KDM4EMEN1KMT2ARENSMN1; SMN2 | |
| SCHEMBL3349978 | 0.79 | DRD2 (0.65) | KDM4EMEN1KMT2ADRD2DRD4 | |
| Toluene SCHEMBL3909886 | 0.77 | CHRM2 (0.54) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Toluene SCHEMBL3908528 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |