Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3902122

C1CC2CCC(C1)N2.O=C(O)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CHRNB2 P17787 5/20 0.35
CHRNA4 P43681 5/20 0.35
CHRNA3 P32297 3/20 0.35
CHRNB3 Q05901 3/20 0.35
CHRNA6 Q15825 3/20 0.35
ATM Q13315 1/20 0.32
ARG1 P05089 1/20 0.32
ARG2 P78540 1/20 0.32
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM3 P20309 2/20 0.32
CHRNA7 P36544 2/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21598159 0.84 KDM4E (0.42) ALDH1A1KDM4ECHRNB2CHRNA4CHRNA3
Trifluoroacetic Acid SCHEMBL939167 0.80 ARG1 (0.34) CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6
Carbamic Acid SCHEMBL5440201 0.78 ALDH1A1 (0.42) ALDH1A1KDM4ECHRNB2CHRNA4CHRNA3
Trifluoroacetic Acid SCHEMBL29158076 0.77 FUCA1 (0.32)
Trifluoroacetic Acid SCHEMBL3762882 0.77 ARG1 (0.39) ALDH1A1KDM4ECHRNB2CHRNA4CHRNA3
Trifluoroacetic Acid SCHEMBL21598176 0.77 KDM1A (0.33) CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6
Trifluoroacetic Acid SCHEMBL30839180 0.77 ARG1 (0.39) ALDH1A1KDM4ECHRNB2CHRNA4CHRNA3
Trifluoroacetic Acid SCHEMBL15995379 0.75 TSHR (0.40) ALDH1A1
Trifluoroacetic Acid SCHEMBL31601887 0.75 CHRNB2 (0.41) CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6
Trifluoroacetic Acid SCHEMBL23234980 0.74 CHRNB2 (0.39) CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1711183-A4 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LTD (GB) 2009-04-01 EP disclosed
EP-1711183-A2 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2006-10-18 EP disclosed
WO-2005067537-A2 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-07-28 WO disclosed