SCHEMBL390267

SCHEMBL390267

C=CC[Sn](CC=C)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.31
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4619452 0.80 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19HTTAKT1
SCHEMBL703693 0.80 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19HTTAKT1
SCHEMBL389681 0.70 TSHR (0.41) ALDH1A1TSHRAKT1
SCHEMBL9759882 0.67 TSHR (0.33) ALDH1A1TSHRCYP2C19HTT
SCHEMBL16735070 0.67 MAOB (0.37) ALDH1A1TSHR
SCHEMBL8659095 0.67 MAOB (0.37) ALDH1A1TSHR
SCHEMBL9274939 0.66 CYP2C19 (0.34) ALDH1A1CYP2C19
SCHEMBL388622 0.65 TSHR (0.41) ALDH1A1TSHRAKT1
SCHEMBL1029950 0.65 TP53 (0.41) ALDH1A1TSHR
SCHEMBL8146117 0.62 ALDH1A1 (0.43) ALDH1A1TSHRAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101697-B2 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2012-01-24 US claimed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US claimed
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS RIMTEC CORPORATION (JP) 2015-03-19 US disclosed
US-8927670-B2 Multicoordinated metal complexes for use in metathesis reactions RIMTEC CORPORATION (JP) 2015-01-06 US disclosed
EP-2397475-B1 4, 4' disubstituted 4H-cyclopentadithiophene and new methods for synthesising the same IMEC (BE) 2014-11-12 EP disclosed
US-20140206793-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-24 US disclosed
US-20140187707-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-03 US disclosed
EP-2749591-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-07-02 EP disclosed
US-8765882-B2 Polythiophene based active layer for solar cells IMEC (BE) 2014-07-01 US disclosed
EP-2740759-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-06-11 EP disclosed
EP-2177562-B1 Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
WO-2007022945-A2 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS VIACATT N.V. (BE) 2007-03-01 WO disclosed
EP-1757613-A1 Multicoordinated metal complexes for use in metathesis reactions Viacatt N.V. (BE) 2007-02-28 EP disclosed
US-20070043188-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS TELENE S.A.S. (FR) 2007-02-22 US disclosed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US disclosed
US-6313232-B1 INTRODUCING INTO REACTOR CONJUGATED DIENE MONOMER OR A MIXTURE OF A CONJUGATED DIENE MONOMER AND A VINYLAROMATIC HYDROCARBON MONOMER IN HYDROCARBON SOLVENT, ORGANOLITHIUM POLYMERIZATION INITIATOR WHILE ADDING TIN COMPOUND TO REACTOR BRIDGESTONE CORPORATION (JP) 2001-11-06 US disclosed
US-5587420-A WEAR RESISTANT, FRICTION RESISTANT TIRE BRIDGESTONE CORPORATION (JP) 1996-12-24 US disclosed
EP-0383002-B1 Coated concrete roof BASF AG (DE) 1994-06-22 EP disclosed
US-5047295-A Hydrazide Crosslinked Addition Interpolymer Containing Tin BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0342493-A2 Tin-containing copolymers, and their use BASF Aktiengesellschaft (DE) 1989-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers VCL, PUF60, JMJD6 ALDH1A1 3595/4885TSHR 4359/4885CYP2C19 3163/4885
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS APEX1, SOD1, AP1M1 ALDH1A1 1713/4885TSHR 4417/4885CYP2C19 3004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.