SCHEMBL388622

SCHEMBL388622

C=C[Sn](C=C)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
AKT1 P31749 1/20 0.33
ALOX15 P16050 1/20 0.31
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL389681 0.77 TSHR (0.41) TSHRALDH1A1AKT1ALOX15TGM2
SCHEMBL8146117 0.72 ALDH1A1 (0.43) TSHRALDH1A1AKT1
Water SCHEMBL8463966 0.67 ALDH1A1 (0.38) TSHRALDH1A1ALOX15
SCHEMBL390267 0.65 ALDH1A1 (0.36) TSHRALDH1A1AKT1
SCHEMBL703693 0.65 ALDH1A1 (0.36) TSHRALDH1A1AKT1
SCHEMBL4619452 0.65 ALDH1A1 (0.36) TSHRALDH1A1AKT1
SCHEMBL376165 0.63 ALDH1A1 (0.40) TSHRALDH1A1ALOX15
SCHEMBL241539 0.63 ALDH1A1 (0.40) TSHRALDH1A1ALOX15
Styrene SCHEMBL1803135 0.63 ALDH1A1 (0.93) TSHRALDH1A1AKT1
SCHEMBL6655700 0.63 ALDH1A1 (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101697-B2 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2012-01-24 US claimed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US claimed
US-4396704-A Solid state devices produced by organometallic plasma developed resists BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1983-08-02 US claimed
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS RIMTEC CORPORATION (JP) 2015-03-19 US disclosed
US-8927670-B2 Multicoordinated metal complexes for use in metathesis reactions RIMTEC CORPORATION (JP) 2015-01-06 US disclosed
EP-2397475-B1 4, 4' disubstituted 4H-cyclopentadithiophene and new methods for synthesising the same IMEC (BE) 2014-11-12 EP disclosed
US-8765882-B2 Polythiophene based active layer for solar cells IMEC (BE) 2014-07-01 US disclosed
US-8450604-B2 Polymerisable compounds for making opto-electronic devices IMEC (BE) 2013-05-28 US disclosed
US-8329923-B2 4, 4′ disubstituted 4H-cyclopentadithiophene and new methods for synthesizing the same IMEC (BE) 2012-12-11 US disclosed
US-20120279569-A1 POLYTHIOPHENE BASED ACTIVE LAYER FOR SOLAR CELLS UNIVERSITEIT HASSELT (BE) 2012-11-08 US disclosed
EP-2509972-A1 POLYMERS COMPRISING 3 -SUBSTITUTED THIOPHENE MOIETIES AS ACTIVE LAYERS FOR SOLAR CELLS IMEC (BE) 2012-10-17 EP disclosed
WO-2010000504-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (BE) 2010-01-07 WO disclosed
US-20080293905-A9 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS RIMTEC CORPORATION (JP) 2008-11-27 US disclosed
WO-2007022945-A2 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS VIACATT N.V. (BE) 2007-03-01 WO disclosed
EP-1757613-A1 Multicoordinated metal complexes for use in metathesis reactions Viacatt N.V. (BE) 2007-02-28 EP disclosed
US-20070043188-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS TELENE S.A.S. (FR) 2007-02-22 US disclosed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US disclosed
US-4500628-A IRRADIATING FILM CONSISTING OF POLYMER AND ORGANOSILICON MONOMER AT&T BELL LABORATORIES (US) 1985-02-19 US disclosed
US-4396704-A Solid state devices produced by organometallic plasma developed resists BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1983-08-02 US disclosed
US-3959412-A Block polymer preparation PHILLIPS PETROLEUM COMPANY (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers VCL, PUF60, JMJD6 TSHR 4359/4885ALDH1A1 3595/4885AKT1 2550/4885
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS APEX1, SOD1, AP1M1 TSHR 4417/4885ALDH1A1 1713/4885AKT1 3246/4885
US-20120279569-A1 POLYTHIOPHENE BASED ACTIVE LAYER FOR SOLAR CELLS SCO2, CLTB, CLTC TSHR 4501/4885ALDH1A1 2933/4885AKT1 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.