Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24567566 | 0.83 | ACACB (0.42) | ALOX5ACACBKDM4EMAPTL3MBTL1 | |
| SCHEMBL2061609 | 0.82 | MAPK14 (0.44) | ACACBPOLBMAPK11MAPK14NPC1 | |
| SCHEMBL9921391 | 0.79 | POLB (0.39) | ACACBKDM4EPOLBMAPK11MAPK14 | |
| SCHEMBL3436120 | 0.79 | CYP1A2 (0.51) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11965637 | 0.76 | MAPK1 (0.40) | KDM4EPOLBMAPTMAPK14NPC1 | |
| SCHEMBL535661 | 0.76 | KDM4E (0.44) | KDM4EPOLBMAPTL3MBTL1MAPK14 | |
| SCHEMBL174225 | 0.76 | RIPK2 (0.51) | KDM4EPOLBMAPK14NPC1RAB9A | |
| SCHEMBL939409 | 0.74 | NPC1 (0.52) | KDM4EPOLBMAPTNPC1RAB9A | |
| SCHEMBL27714949 | 0.74 | PROKR1 (0.39) | KDM4EPOLBMAPTMAPK14NPC1 | |
| SCHEMBL22336048 | 0.71 | RAB9A (0.39) | KDM4EL3MBTL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560564-B2 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-14 | — | — | US | disclosed |
| CN-100352808-C | Heterocyclic diamide invertebrate pest control agents | DU PONT (US) | 2007-12-05 | — | — | CN | disclosed |
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | ANNIS GARY D | 2006-09-14 | — | — | US | disclosed |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-05-27 | — | — | US | disclosed |
| CN-1494530-A | Heterocyclic diamide invertebrate pest control agents | �Ű˾ | 2004-05-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205748-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, C1S | ALOX5 1633/4885ACACB 4311/4885KDM4E 1378/4885 |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, DDC | ALOX5 976/4885ACACB 4268/4885KDM4E 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.