Epicatechin Gallate

Epicatechin Gallate

SCHEMBL39046

O=C(OC1Cc2c(O)cc(O)cc2OC1c1ccc(O)c(O)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 7/20 1.00
BACE1 P56817 5/20 1.00
BCL2 P10415 4/20 1.00
PSMB5 P28074 4/20 1.00
SNCA P37840 4/20 1.00
PGD P52209 4/20 1.00
PKM P14618 3/20 1.00
MET P08581 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 3/20 1.00
MAPT P10636 3/20 1.00
RECQL P46063 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
APP P05067 2/20 1.00
ADAMTS4 O75173 2/20 1.00
SLCO2B1 O94956 2/20 1.00
CNR1 P21554 2/20 1.00
CNR2 P34972 2/20 1.00
RAD52 P43351 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epicatechin Gallate SCHEMBL30977096 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
(-)-Catechingallate SCHEMBL31181360 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
(-)-Catechingallate SCHEMBL4639342 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL39047 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL4639313 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL13014548 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Catechin Gallate SCHEMBL145289 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL4545330 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL8426343 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL31297152 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12194 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636311-B2 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation GALLEON LABS LLC (US) 2026-05-26 US claimed
EP-4743071-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE INC. (US) 2026-05-20 EP claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
CN-122063058-A Fixation time determining method and related device based on non-volatile compound analysis 贵州大学 2026-05-19 CN claimed
CN-122031747-A Mesoscopic phase enhanced polyphenol-based aggregate adhesive and preparation method thereof 华南理工大学 2026-05-15 CN claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
EP-4739275-A1 VITELLARIA PARADOXA EXTRACT COMPOSITION Bunge Loders Croklaan B.V. (NL) 2026-05-13 EP claimed
CN-122005161-A Antibacterial anti-inflammatory bile duct support 义乌中复新材料科技有限公司 2026-05-12 CN claimed
EP-4734961-A1 NEW METHOD OF PRODUCING AN AQUEOUS MESOPARTICLE COMPOSITION COMPRISING A LIPOPHILIC COMPOUND BIOGNTX R&D B.V. (NL) 2026-05-06 EP claimed
WO-2026087667-A1 METHOD OF MODIFICATION OF WHEY PROTEIN AT ACIDIC PH BY REACTION WITH OXIDIZED PHENOLIC COMPOUNDS, THE MODIFIED PROTEIN COMPOSITION, AND NUTRITIONAL USES OF THE MODIFIED PROTEIN COMPOSITION ARLA FOODS AMBA (DK) 2026-04-30 WO claimed
US-5137922-A METHOD FOR INHIBITING AND TREATING INFECTION CAUSED BY INFLUENZA VIRUS MITSUI NORIN CO., LTD. (JP) 1992-08-11 US claimed
US-5104901-A Orally administering tea polyphenol; theaflavin, catechin, epigallocatechin gallate MITSUI NORIN CO., LTD. (JP) 1992-04-14 US claimed
EP-0443090-A2 Agent for preventing infection with methicillin-resistant staphylococcus MITSUI NORIN CO., LTD. (JP) 1991-08-28 EP claimed
EP-0423419-A1 Inhibitive agent against activity of alpha-amylase MITSUI NORIN CO., LTD. (JP) 1991-04-24 EP claimed
EP-0417385-A2 Preventive and curative medicament against infection with influenza virus, containing tea or tea polyphenols MITSUI NORIN CO., LTD. (JP) 1991-03-20 EP claimed
EP-0415126-A1 Anti-dental plaque agents MITSUI NORIN CO., LTD. (JP) 1991-03-06 EP claimed
EP-0397914-A1 Antitoxins for bacterial exotoxins MITSUI NORIN CO., LTD. (JP) 1990-11-22 EP claimed
US-4613672-A SOLVENT EXTRACTION MITSU NORIN CO., LTD. (JP) 1986-09-23 US claimed
US-4517175-A FLAVANOL DERIVATIVES AND PROTEINS KAO CORPORATION (JP) 1985-05-14 US claimed
US-4248789-A MIXING CAFFEINE SOLUTION WITH TANNIC SOLUTION EXTRACTED FROM TEA DIRECTOR OF NATIONAL RESEARCH INSTITUTE OF TEA (JP) 1981-02-03 US claimed