(-)-Catechingallate

(-)-Catechingallate

SCHEMBL4639342

O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c1ccc(O)c(O)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 7/20 1.00
BACE1 P56817 5/20 1.00
BCL2 P10415 4/20 1.00
PSMB5 P28074 4/20 1.00
SNCA P37840 4/20 1.00
PGD P52209 4/20 1.00
PKM P14618 3/20 1.00
MET P08581 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 3/20 1.00
MAPT P10636 3/20 1.00
RECQL P46063 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
APP P05067 2/20 1.00
ADAMTS4 O75173 2/20 1.00
SLCO2B1 O94956 2/20 1.00
CNR1 P21554 2/20 1.00
CNR2 P34972 2/20 1.00
RAD52 P43351 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epicatechin Gallate SCHEMBL30977096 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL39046 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
(-)-Catechingallate SCHEMBL31181360 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL39047 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL4639313 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL13014548 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Catechin Gallate SCHEMBL145289 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL4545330 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL8426343 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL31297152 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122042866-A Method for separating, detecting and identifying flavonoid component in cocoa 中国热带农业科学院香料饮料研究所 2026-05-15 CN claimed
EP-4622629-A1 METHOD FOR TREATING AND/OR PREVENTING EDEMATOUS FIBROSCLEROTIC PANNICULOPATHY Caliway Biopharmaceuticals Co. Ltd. (TW) 2025-10-01 EP claimed
EP-3381451-B1 PHARMACEUTICAL COMPOSITION USED FOR REDUCING LOCALISED FAT AND USE OF PHARMACEUTICAL COMPOSITION CALIWAY BIOPHARMACEUTICALS CO LTD (TW) 2025-08-20 EP claimed
US-20250041375-A1 SUGAR CANE EXTRACTS FOR USE IN ANIMAL FEEDS Poly Gain Pte Ltd (SG) 2025-02-06 US claimed
US-20240358740-A1 FOLIC COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC NEUROPATHIES CROSS III WILLIAM H (US) 2024-10-31 US claimed
US-20240350574-A1 PHENOLIC PHYTOCHEMICALS FOR BONE METASTASIS OF CANCER NDSU RESEARCH FOUNDATION 2024-10-24 US claimed
CN-118581042-A NK cell culture system and method for in vitro culture of NK cells 深圳市济因生物科技有限公司 2024-09-03 CN claimed
EP-4408480-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE The Regents Of The University Of Michigan (US) 2024-08-07 EP claimed
US-12029750-B2 Folic compositions and methods for treatment of diabetic neuropathies CROSS III WILLIAM H (US) 2024-07-09 US claimed
WO-2024109276-A1 METHOD FOR TREATING AND/OR PREVENTING EDEMATOUS FIBROSCLEROTIC PANNICULOPATHY CALIWAY BIOPHARMACEUTICALS CO., LTD. (CN) 2024-05-30 WO claimed
EP-4188408-A1 A STANDARDIZED BIOFLAVONOID COMPOSITION FOR REGULATION OF HOMEOSTASIS OF HOST DEFENSE MECHANISM Unigen, Inc. (US) 2023-06-07 EP claimed
EP-3378506-B1 DRUG RELEASING COATINGS FOR MEDICAL DEVICES LUTONIX INC (US) 2023-06-07 EP claimed
US-20230157342-A1 TASTE OF CONSUMABLES THE PRODUCT MAKERS (AUSTRALIA) PTY LTD (AU) 2023-05-25 US claimed
WO-2023056427-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-04-06 WO claimed
CN-115902030-A Method for identifying natural fruit juice based on 9 phenolic compounds 宝健(北京)生物技术有限公司 2023-04-04 CN claimed
CN-110801445-B Composition containing benzo-hydropyranol derivative and emodin type anthraquinone compound, and dosage form and application thereof 中山万远新药研发有限公司 2023-03-21 CN claimed
CN-110859830-B Composition containing benzo-hydropyranol derivative and alizarin type anthraquinone compound, and dosage form and application thereof 中山万远新药研发有限公司 2023-03-21 CN claimed
US-20220305047-A1 FOLIC COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC NEUROPATHIES CROSS III WILLIAM H (US) 2022-09-29 US claimed
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-10 US claimed
EP-3463276-B1 PROCESS FOR TREATING HAIR KAO GERMANY GMBH (DE) 2022-03-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE MYD88, STING1, TLR3 DYRK1A 3665/4885BACE1 3367/4885BCL2 2321/4885
US-12029750-B2 Folic compositions and methods for treatment of diabetic neuropathies FOLR2, FPGS, DHFR DYRK1A 558/4885BACE1 2387/4885BCL2 618/4885
US-20240358740-A1 FOLIC COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC NEUROPATHIES FOLR2, FPGS, DHFR DYRK1A 558/4885BACE1 2387/4885BCL2 618/4885
US-20220305047-A1 FOLIC COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC NEUROPATHIES FOLR2, FPGS, DHFR DYRK1A 558/4885BACE1 2387/4885BCL2 618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.