Catechin Gallate

Catechin Gallate

SCHEMBL145289

O=C(O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 7/20 1.00
BACE1 P56817 5/20 1.00
BCL2 P10415 4/20 1.00
PSMB5 P28074 4/20 1.00
SNCA P37840 4/20 1.00
PGD P52209 4/20 1.00
PKM P14618 3/20 1.00
MET P08581 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 3/20 1.00
MAPT P10636 3/20 1.00
RECQL P46063 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
APP P05067 2/20 1.00
ADAMTS4 O75173 2/20 1.00
SLCO2B1 O94956 2/20 1.00
CNR1 P21554 2/20 1.00
CNR2 P34972 2/20 1.00
RAD52 P43351 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epicatechin Gallate SCHEMBL30977096 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL39046 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
(-)-Catechingallate SCHEMBL31181360 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
(-)-Catechingallate SCHEMBL4639342 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL39047 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL4639313 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL13014548 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL4545330 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL8426343 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA
Epicatechin Gallate SCHEMBL31297152 1.00 DYRK1A (1.00) DYRK1ABACE1BCL2PSMB5SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087667-A1 METHOD OF MODIFICATION OF WHEY PROTEIN AT ACIDIC PH BY REACTION WITH OXIDIZED PHENOLIC COMPOUNDS, THE MODIFIED PROTEIN COMPOSITION, AND NUTRITIONAL USES OF THE MODIFIED PROTEIN COMPOSITION ARLA FOODS AMBA (DK) 2026-04-30 WO claimed
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
EP-4697979-A1 METHOD OF PRODUCING A MODIFIED PROTEIN COMPOSITION BY REACTION WITH OXIDIZED PHENOLIC COMPOUNDS, THE MODIFIED PROTEIN COMPOSITION, AND NUTRITIONAL USES OF THE MODIFIED PROTEIN COMPOSITION Arla Foods amba (DK) 2026-02-25 EP claimed
EP-4340640-B1 HIGH PROTEIN, MICELLAR CASEIN-CONTAINING NUTRITIONAL LIQUIDS ENRICHED WITH CATECHIN-COMPOUNDS AND METHOD OF PRODUCTION ARLA FOODS AMBA (DK) 2026-02-04 EP claimed
US-20250275566-A1 HIGH PROTEIN, MICELLAR CASEIN-CONTAINING NUTRITIONAL LIQUIDS ENRICHED WITH CATECHIN-COMPOUNDS AND METHOD OF PRODUCTION ARLA FOODS AMBA (DK) 2025-09-04 US claimed
US-12364728-B2 Composition for reducing body fat comprising green tea extract containing gallocatechin gallate as an active ingredient and manufacturing method thereof AMOREPACIFIC CORPORATION (KR) 2025-07-22 US claimed
WO-2025096874-A1 COMPOUNDS AND METHODS FOR USING GALLOYLATED POLYPHENOLS TO TREAT DISEASES MEDIATED BY THIOL ISOMERASES BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2025-05-08 WO claimed
US-20250134853-A1 COMPOUNDS AND METHODS FOR USING GALLOYLATED POLYPHENOLS TO TREAT DISEASES MEDIATED BY THIOL ISOMERASES BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2025-05-01 US claimed
US-12208128-B2 Compositions and methods for treating traveler's diarrhea ARTESA LLC (US) 2025-01-28 US claimed
US-20250011393-A1 FLAVONOID-COLLAGEN CROSSLINKED ANTIOXIDANT HYDROGEL NORTH CAROLINA STATE UNIVERSITY 2025-01-09 US claimed
WO-2013184884-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORPORATION (US) 2013-12-12 WO claimed
EP-2670392-A2 CAROTENOID PARTICLES AND USES THEREOF IP Science Limited (GB) 2013-12-11 EP claimed
WO-2013090884-A1 BRADYRHIZOBIUM STRAINS Novozymes Biologicals Holdings A/S (DK) 2013-06-20 WO claimed
WO-2012104576-A2 CAROTENOID PARTICLES AND USES THEREOF IP SCIENCE LIMITED (GB) 2012-08-09 WO claimed
WO-2012095388-A2 COMPOUNDS FOR TREATMENT OF FELINE LEUKEMIA IN FELIDAE Universität Zürich (CH) 2012-07-19 WO claimed
CN-102014636-A Methods of treating cardiovascular disorders associated with atherosclerosis AMCOL INTERNATIONAL CORP 2011-04-13 CN claimed
US-20090098254-A1 Methods And Compositions For Improving Sensory And Shelf Life Characteristics Of Raw Meat Products TYSON FOODS, INC. 2009-04-16 US claimed
CN-1192772-C Application of epigallic catechin 3-gallate in treating HPV infection XINGLIN TRADITIONAL CHINESE ME (CN) 2005-03-16 CN claimed
CN-1413117-A Drugs, drinks or foods TAKARA SHUZO CO (JP) 2003-04-23 CN claimed
CN-1382437-A Application of epigallic catechin 3-gallate in treating HPV infection XINGLIN TRADITIONAL CHINESE ME (CN) 2002-12-04 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250134853-A1 COMPOUNDS AND METHODS FOR USING GALLOYLATED POLYPHENOLS TO TREAT DISEASES MEDIATED BY THIOL ISOMERASES GGT1, SPR, PON1 DYRK1A 4402/4885BACE1 4538/4885BCL2 3186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.