Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 1.00 |
| ▸ | BACE1 | P56817 | 5/20 | 1.00 |
| ▸ | BCL2 | P10415 | 4/20 | 1.00 |
| ▸ | PSMB5 | P28074 | 4/20 | 1.00 |
| ▸ | SNCA | P37840 | 4/20 | 1.00 |
| ▸ | PGD | P52209 | 4/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | MET | P08581 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | APP | P05067 | 2/20 | 1.00 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 1.00 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 1.00 |
| ▸ | CNR1 | P21554 | 2/20 | 1.00 |
| ▸ | CNR2 | P34972 | 2/20 | 1.00 |
| ▸ | RAD52 | P43351 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epicatechin Gallate SCHEMBL30977096 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| Epicatechin Gallate SCHEMBL39046 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| (-)-Catechingallate SCHEMBL31181360 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| (-)-Catechingallate SCHEMBL4639342 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| Epicatechin Gallate SCHEMBL39047 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| Epicatechin Gallate SCHEMBL13014548 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| Catechin Gallate SCHEMBL145289 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| Epicatechin Gallate SCHEMBL4545330 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| Epicatechin Gallate SCHEMBL8426343 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA | |
| Epicatechin Gallate SCHEMBL31297152 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1BCL2PSMB5SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030283-B2 | Food packaging film with antioxidant for freshness protection | INTEPLAST GROUP CORPORATION (US) | 2024-07-09 | — | — | US | claimed |
| CN-119868522-A | Broad-spectrum multivalent tumor cell vaccine, and preparation method and application thereof | 华南理工大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-115803074-B | Medicine vaporizing inhaler | 杰迪克斯帕马株式会社 | 2025-02-14 | — | — | CN | disclosed |
| US-12030283-B2 | Food packaging film with antioxidant for freshness protection | INTEPLAST GROUP CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| CN-115803074-A | Medicine vaporization inhaler | 杰迪克斯帕马株式会社 | 2023-03-14 | — | — | CN | disclosed |
| WO-2023002500-A1 | SINGLE PROCESS FOR SEQUENTIAL EXTRACTION OF PRODUCTS FROM GREEN TEA LEAVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-01-26 | — | — | WO | disclosed |
| US-20180000774-A1 | METHODS OF TREATING COGNITIVE AND BEHAVIORAL IMPAIRMENT IN DOWN SYNDROME AND ALZHEIMERS DISEASE PATIENTS | AVANTI BIOSCIENCES, INC (US) | 2018-01-04 | — | — | US | disclosed |
| US-20160068503-A1 | (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2016-03-10 | — | — | US | disclosed |
| US-9169230-B2 | (−)-Epigallocatechin gallate derivatives for inhibiting proteasome | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2015-10-27 | — | — | US | disclosed |
| US-8859290-B2 | Inhibitors of influenza endonuclease activity and tools for their discovery | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-10-14 | — | — | US | disclosed |
| US-8710248-B2 | (−)-epigallocatechin gallate derivatives for inhibiting proteasome | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-04-29 | — | — | US | disclosed |
| US-20130090300-A1 | INHIBITORS OF INFLUENZA ENDONUCLEASE ACTIVITY AND TOOLS FOR THEIR DISCOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-04-11 | — | — | US | disclosed |
| US-20130090300-A1 | INHIBITORS OF INFLUENZA ENDONUCLEASE ACTIVITY AND TOOLS FOR THEIR DISCOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-04-11 | — | — | US | disclosed |
| US-20120232135-A1 | (-)-Epigallocatechin Gallate Derivatives for Inhibiting Proteasome | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2012-09-13 | — | — | US | disclosed |
| US-8193377-B2 | (−)-epigallocatechin gallate derivatives for inhibiting proteasome | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2012-06-05 | — | — | US | disclosed |
| EP-1778663-A4 | (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME | UNIV HONG KONG POLYTECHNIC (CN) | 2008-08-06 | — | — | EP | disclosed |
| US-20080176931-A1 | e.g. 5,7-Bis(benzyloxy)-2-[3,4,5-tris(benzyloxy)phenyl]chroman-3-yl 3-(benzyloxy)benzoate; antiproliferative, antitumor agent; reducing tumor cell growth; more potent, better bioavailability than catechin | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-07-24 | — | — | US | disclosed |
| EP-1778663-A1 | (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME | The Hong Kong Polytechnic University (CN) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006017981-A9 | (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME | UNIV HONG KONG POLYTECHNIC (CN) | 2006-05-11 | — | — | WO | disclosed |
| WO-2006017981-A1 | (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232135-A1 | (-)-Epigallocatechin Gallate Derivatives for Inhibiting Proteasome | PSMC1, PSME1, PSMB1 | DYRK1A 4641/4885BACE1 1077/4885BCL2 400/4885 |
| US-20130090300-A1 | INHIBITORS OF INFLUENZA ENDONUCLEASE ACTIVITY AND TOOLS FOR THEIR DISCOVERY | DNASE1, ENDOD1, RNASEH1 | DYRK1A 2861/4885BACE1 277/4885BCL2 4092/4885 |
| US-20180000774-A1 | METHODS OF TREATING COGNITIVE AND BEHAVIORAL IMPAIRMENT IN DOWN SYNDROME AND ALZHEIMERS DISEASE PATIENTS | CHAT, CAMK2A, CAMK1G | DYRK1A 49/4885BACE1 132/4885BCL2 1640/4885 |
| US-20160068503-A1 | (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME | PSMC1, PSME1, PSMB1 | DYRK1A 4641/4885BACE1 1077/4885BCL2 400/4885 |
| US-20080176931-A1 | e.g. 5,7-Bis(benzyloxy)-2-[3,4,5-tris(benzyloxy)phenyl]chroman-3-yl 3-(benzyloxy)benzoate; antiproliferative, antitumor agent; reducing tumor cell growth; more potent, better bioavailability than catechin | UBE2G2, C9, BAP1 | DYRK1A 4869/4885BACE1 2980/4885BCL2 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.