Decursin

Decursin

SCHEMBL3904733

CC(C)=CC(=O)OC1Cc2cc3ccc(=O)oc3cc2OC1(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 1.00
▸ GAA P10253 3/20 0.65
▸ ACHE P22303 2/20 0.65
▸ MGAM O43451 1/20 0.65
▸ SI P14410 1/20 0.65
▸ PTPN1 P18031 1/20 0.65
▸ MGAM2 Q2M2H8 1/20 0.65
▸ KDM4E B2RXH2 10/20 0.48
▸ HPGD P15428 8/20 0.48
▸ ALDH1A1 P00352 8/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ HSD17B10 Q99714 3/20 0.48
▸ CYP3A4 P08684 2/20 0.48
▸ LMNA P02545 2/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ NPC1 O15118 1/20 0.46
▸ CA9 Q16790 2/20 0.42
▸ RCE1 Q9Y256 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decursin SCHEMBL29912722 1.00 MAOA (1.00) MAOAGAAACHEMGAMSI
Decursin SCHEMBL14511556 1.00 MAOA (1.00) MAOAGAAACHEMGAMSI
SCHEMBL4740846 0.88 MAOA (0.79) MAOAGAAACHEMGAMSI
SCHEMBL14303567 0.88 MAOA (0.79) MAOAGAAACHEMGAMSI
Decursinol Angelate SCHEMBL14310264 0.87 MAOA (0.76) MAOAGAAACHEMGAMSI
Decursinol Angelate SCHEMBL4740622 0.87 MAOA (0.76) MAOAGAAACHEMGAMSI
Decursinol Angelate SCHEMBL3901157 0.87 MAOA (0.76) MAOAGAAACHEMGAMSI
Decursinol Angelate SCHEMBL3901154 0.87 MAOA (0.76) MAOAGAAACHEMGAMSI
SCHEMBL14105695 0.84 MAOA (0.73) MAOAGAAACHEMGAMSI
Dihydropyranocoumarin D2 SCHEMBL4714192 0.84 MAOA (0.72) MAOAGAAACHEMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1169034-A4 DECURSINOL OR DERIVATIVE THEREOF AS ANALGESIC AGENT SCIGENIC CO LTD (KR) 2009-03-18 — — EP claimed
EP-1169034-A1 DECURSINOL OR DERIVATIVE THEREOF AS ANALGESIC AGENT Scigenic Co., Ltd. (KR) 2002-01-09 — — EP claimed
WO-2001052841-A1 DECURSINOL OR DERIVATIVE THEREOF AS ANALGESIC AGENT SCIGENIC CO., LTD. (KR) 2001-07-26 — — WO claimed
US-20230248791-A1 METHODS FOR MANUFACTURING ANGELICA GIGAS NAKAI EXTRACT USING FERMENTATION BACTERIA SOOY-K CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230248791-A1 METHODS FOR MANUFACTURING ANGELICA GIGAS NAKAI EXTRACT USING FERMENTATION BACTERIA SOOY-K CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230248791-A1 METHODS FOR MANUFACTURING ANGELICA GIGAS NAKAI EXTRACT USING FERMENTATION BACTERIA SOOY-K CO., LTD. (KR) 2023-08-10 — — US disclosed
WO-2010064817-A2 NOVEL COUMARIN-BASED COMPOUNDS, PREPARATION METHOD THEREOF, AND MULTIDRUG RESISTANCE INHIBITORY PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENTS 한국생명공학연구원 (KR) 2010-06-10 — — WO disclosed
EP-1169034-A4 DECURSINOL OR DERIVATIVE THEREOF AS ANALGESIC AGENT SCIGENIC CO LTD (KR) 2009-03-18 — — EP disclosed
EP-1169034-A1 DECURSINOL OR DERIVATIVE THEREOF AS ANALGESIC AGENT Scigenic Co., Ltd. (KR) 2002-01-09 — — EP disclosed
WO-2001052841-A1 DECURSINOL OR DERIVATIVE THEREOF AS ANALGESIC AGENT SCIGENIC CO., LTD. (KR) 2001-07-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248791-A1 METHODS FOR MANUFACTURING ANGELICA GIGAS NAKAI EXTRACT USING FERMENTATION BACTERIA CUTA, SHARPIN, GABRE MAOA 293/4885GAA 525/4885ACHE 559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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