Decursinol Angelate

Decursinol Angelate

SCHEMBL14310264

C/C=C(/C)C(=O)O[C@H]1Cc2cc3ccc(=O)oc3cc2OC1(C)C

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.76
▸ KDM4E B2RXH2 12/20 0.65
▸ HPGD P15428 10/20 0.65
▸ HSD17B10 Q99714 3/20 0.65
▸ CYP3A4 P08684 2/20 0.65
▸ GAA P10253 4/20 0.64
▸ ACHE P22303 2/20 0.64
▸ MGAM O43451 1/20 0.64
▸ SI P14410 1/20 0.64
▸ PTPN1 P18031 1/20 0.64
▸ MGAM2 Q2M2H8 1/20 0.64
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ ALDH1A1 P00352 11/20 0.58
▸ LMNA P02545 3/20 0.52
▸ HTT P42858 2/20 0.52
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ RCE1 Q9Y256 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decursinol Angelate SCHEMBL3901157 1.00 MAOA (0.76) MAOAKDM4EHPGDHSD17B10CYP3A4
Decursinol Angelate SCHEMBL3901154 1.00 MAOA (0.76) MAOAKDM4EHPGDHSD17B10CYP3A4
Decursinol Angelate SCHEMBL4740622 1.00 MAOA (0.76) MAOAKDM4EHPGDHSD17B10CYP3A4
SCHEMBL14105695 0.90 MAOA (0.73) MAOAKDM4EHPGDHSD17B10CYP3A4
SCHEMBL14303567 0.89 MAOA (0.79) MAOAKDM4EHPGDHSD17B10CYP3A4
SCHEMBL4740846 0.89 MAOA (0.79) MAOAKDM4EHPGDHSD17B10CYP3A4
SCHEMBL31046705 0.88 MAOA (0.69) MAOAKDM4EHPGDHSD17B10CYP3A4
SCHEMBL31046691 0.88 MAOA (0.69) MAOAKDM4EHPGDHSD17B10CYP3A4
Decursin SCHEMBL14511556 0.87 MAOA (1.00) MAOAKDM4EHPGDHSD17B10CYP3A4
Decursin SCHEMBL3904733 0.87 MAOA (1.00) MAOAKDM4EHPGDHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082502-A Method for differentiating pluripotent stem cells into insulin-secreting cells 广西中医药大学附属瑞康医院(广西中西医结合医院) 2025-06-03 — — CN claimed
US-20250000926-A1 METHOD FOR PREVENTING, IMPROVING OR TREATING INFLAMMATORY SKIN DISEASE COMPRISING A COMPOSITION COMPRISING A FERMENTED ANGELICA GIGAS EXTRACT SOOY-K CO., LTD. (KR) 2025-01-02 — — US claimed
CN-118685346-A Small molecule culture medium for liver organoid amplification and application thereof 山东大学 2024-09-24 — — CN claimed
US-20240115678-A1 PERSONALIZED MULTIDISCIPLINARY CANCER THERAPY VELTMEYER JAMES (US) 2024-04-11 — — US claimed
WO-2024026505-A2 DISRUPTION OF TELOCYTE ACTIVITY PATEL AMIT (US) 2024-02-01 — — WO claimed
US-20230201215-A1 DRUG COMBINATIONS FOR INHIBITING INFECTIVITY OF INFLUENZA AND CORONA VIRUSES SYSTAMEDIC INC. (US) 2023-06-29 — — US claimed
CN-113101308-B Angelica gigas nakai extract and preparation method and application thereof 吉林大学珠海学院 2022-09-13 — — CN claimed
CN-122005983-A Loess cupping glass for medical use and preparation method thereof 延边朝鲜族自治州朝医医院(延边朝鲜族自治州第二人民医院、延边朝鲜族自治州肿瘤医院) 2026-05-12 — — CN disclosed
US-20260048093-A1 COMBINATION THERAPY OF MIXED HERBAL EXTRACT AND DOCETAXEL FOR PREVENTING OR TREATING CANCER JAEIN R&P INC. (KR) 2026-02-19 — — US disclosed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 — — US disclosed
US-20250367229-A1 Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof MITOPOWER LLC (US) 2025-12-04 — — US disclosed
CN-120082502-A Method for differentiating pluripotent stem cells into insulin-secreting cells 广西中医药大学附属瑞康医院(广西中西医结合医院) 2025-06-03 — — CN disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 — — US disclosed
CN-113101308-B Angelica gigas nakai extract and preparation method and application thereof 吉林大学珠海学院 2022-09-13 — — CN disclosed
CN-114668829-A Radix stephaniae tetrandrae and radix astragali composition for inhibiting COX-2 activity and preparation method and application thereof 北京尚捷优蓝科技有限公司 2022-06-28 — — CN disclosed
WO-2022090819-A1 NON-TOXIC FUROCOUMARIN-RICH PLANT EXTRACTS AND RELATED COMPOSITIONS FOR USE AS ANTIMICROBIAL SUBSTANCE OR MEDICAMENT AND OTHER THERAPEUTIC USES ICE-P LIFE, S.L. (ES) 2022-05-05 — — WO disclosed
EP-3986420-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES Mitopower LLC (US) 2022-04-27 — — EP disclosed
US-11286274-B2 Nicotinamide riboside derivatives and their uses MITOPOWER LLC (US) 2022-03-29 — — US disclosed
US-20220062314-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES MitoPower, LLC (US) 2022-03-03 — — US disclosed
WO-2008004817-A1 NOVEL DECURSIN DERIVATIVES AND THE USE THEREOF PARK YONG JIN (KR) 2008-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048093-A1 COMBINATION THERAPY OF MIXED HERBAL EXTRACT AND DOCETAXEL FOR PREVENTING OR TREATING CANCER EGFR, ERBB2, TTBK2 MAOA 4425/4885KDM4E 3974/4885HPGD 4314/4885
US-20220062314-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES NADK, NNT, NAMPT MAOA 486/4885KDM4E 3520/4885HPGD 134/4885
US-11286274-B2 Nicotinamide riboside derivatives and their uses NME4, NADK, NQO1 MAOA 484/4885KDM4E 3963/4885HPGD 133/4885
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO MAOA 471/4885KDM4E 1457/4885HPGD 1052/4885
US-20250367229-A1 Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof NQO1, DOHH, DHODH MAOA 1179/4885KDM4E 3542/4885HPGD 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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