Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288510 | 0.78 | SLC22A6 (0.50) | SLC22A6GABRR1LMNATDP1CACNA2D1 | |
| SCHEMBL10618410 | 0.77 | SLC22A6 (0.46) | SLC22A6GABRR1LMNATDP1CACNA2D1 | |
| SCHEMBL22693646 | 0.77 | SLC22A6 (0.46) | SLC22A6GABRR1LMNATDP1CACNA2D1 | |
| Hydrochloric Acid SCHEMBL7372643 | 0.75 | SLC22A6 (0.47) | SLC22A6GABRR1LMNATDP1CACNA2D1 | |
| SCHEMBL6734053 | 0.75 | SLC22A6 (0.47) | SLC22A6GABRR1LMNATDP1SMN1; SMN2 | |
| SCHEMBL28799207 | 0.75 | SLC22A6 (0.47) | SLC22A6GABRR1LMNATDP1CACNA2D1 | |
| SCHEMBL288273 | 0.75 | CACNA2D1 (0.56) | LMNATDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL60920 | 0.75 | GABRP (0.46) | SLC22A6GABRR1LMNATDP1CACNA2D1 | |
| SCHEMBL2377939 | 0.75 | CACNA2D1 (0.56) | LMNATDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL397004 | 0.75 | GABRP (0.46) | SLC22A6GABRR1LMNATDP1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084137-A1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2001-03-21 | — | — | EP | claimed |
| WO-1999064442-A1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI S.P.A. (IT) | 1999-12-16 | — | — | WO | claimed |
| EP-1084137-B1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-02-18 | — | — | EP | disclosed |