Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953788 | 1.00 | PPARA (0.55) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL693646 | 1.00 | PPARA (0.55) | PPARACTSKKLK7KLK5SYK | |
| Alcohol SCHEMBL692835 | 0.98 | CTSK (0.55) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL5970352 | 0.96 | KLK7 (0.54) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL8615707 | 0.96 | KLK7 (0.54) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL1094804 | 0.93 | PPARA (0.57) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL13205156 | 0.93 | PPARA (0.57) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL1094803 | 0.93 | PPARA (0.57) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL7222412 | 0.90 | SYK (0.55) | PPARACTSKKLK7KLK5SYK | |
| SCHEMBL5970655 | 0.90 | SYK (0.55) | PPARACTSKKLK7KLK5SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180438-A1 | 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS | Cancer Targeted Technology LLC (US) | 2023-05-17 | — | — | EP | disclosed |
| EP-3560937-A1 | 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS | Cancer Targeted Technology LLC (US) | 2019-10-30 | — | — | EP | disclosed |
| US-9566312-B2 | Cyclic peptides and use as medicines | NOVARTIS AG (CH) | 2017-02-14 | — | — | US | disclosed |
| US-20150306172-A1 | CYCLIC PEPTIDES AND USE AS MEDICINES | NOVARTIS AG (CH) | 2015-10-29 | — | — | US | disclosed |
| EP-2809655-B1 | BENZIIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AS SODIUM CHANNEL MODULATORS | PFIZER (US) | 2015-08-12 | — | — | EP | disclosed |
| US-9072696-B2 | Cyclic peptides and use as medicines | NOVARTIS AG (CH) | 2015-07-07 | — | — | US | disclosed |
| US-8927587-B2 | Chemical compounds | PFIZER LIMITED (GB) | 2015-01-06 | — | — | US | disclosed |
| US-20140134132-A1 | CYCLIC PEPTIDES AND USE AS MEDICINES | NOVARTIS AG (CH) | 2014-05-15 | — | — | US | disclosed |
| US-20130274243-A1 | Chemical Compounds | PFIZER LTD (GB) | 2013-10-17 | — | — | US | disclosed |
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| WO-1998050421-A1 | ANALGESIC PEPTIDOMIMETIC COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274243-A1 | Chemical Compounds | SCN8A, SCN5A, KCNJ8 | PPARA 4206/4885CTSK 2785/4885KLK7 3066/4885 |
| US-20140134132-A1 | CYCLIC PEPTIDES AND USE AS MEDICINES | PPIF, VIP, FKBP1B | PPARA 3576/4885CTSK 3379/4885KLK7 3469/4885 |
| US-20150306172-A1 | CYCLIC PEPTIDES AND USE AS MEDICINES | PPIF, VIP, MAVS | PPARA 3310/4885CTSK 3303/4885KLK7 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.