SCHEMBL3907415

SCHEMBL3907415

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C2c1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
NPSR1 Q6W5P4 4/20 0.44
CYP3A4 P08684 3/20 0.44
NPC1 O15118 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CASP1 P29466 2/20 0.44
BRCA1 P38398 2/20 0.44
HTT P42858 2/20 0.44
CASP7 P55210 2/20 0.44
USP2 O75604 2/20 0.44
GAA P10253 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TSHR P16473 1/20 0.44
HBB P68871 1/20 0.44
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396807 0.87 CYP3A4 (0.45) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL21396497 0.86 CYP3A4 (0.42) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL4070707 0.84 NPC1 (0.45) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL3896874 0.84 LMNA (0.46) MEN1KMT2ANPSR1NPC1CYP2C9
SCHEMBL21168242 0.82 CYP3A4 (0.42) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL82135 0.81 MEN1 (0.52) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL18179775 0.81 MEN1 (0.43) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL21396616 0.81 KDM1A (0.38) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL30539519 0.79 CYP2C9 (0.59) MEN1KMT2ANPSR1CYP3A4NPC1
SCHEMBL10082360 0.79 CYP2C9 (0.59) MEN1KMT2ANPSR1CYP3A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182315-A1 COLORED CURABLE RESIN COMPOSITION, COLOR FILTER, AND DISPLAY DEVICE 동우 화인켐 주식회사 2019-09-26 WO disclosed
EP-1765592-B1 METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-01-28 EP disclosed
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
EP-1614541-A2 Method of making a lithographic printing plate. Agfa-Gevaert (BE) 2006-01-11 EP disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed